Electrical Stimulation in the Bone Repair of Defects Created in Rabbit Skulls

Electrical stimulation has been used in different conditions for tissue regeneration. The aim of this study was to analyze the tissue response of defects created in rabbit skulls to electrical stimulation. Two groups were formed, each with 9 New Zealand rabbits; two 5 mm defects were made, one in ea...

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Autores principales:	Silva,C, Olate,S, Pozzer,L, Muñoz,M, Cantín,M, Uribe,F, de Albergaría-Barbosa,J. R
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2015
Materias:	Electrical stimulus Bone regeneration Bone graft
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000300054
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spelling	oai:scielo:S0717-950220150003000542015-12-04Electrical Stimulation in the Bone Repair of Defects Created in Rabbit SkullsSilva,COlate,SPozzer,LMuñoz,MCantín,MUribe,Fde Albergaría-Barbosa,J. R Electrical stimulus Bone regeneration Bone graft Electrical stimulation has been used in different conditions for tissue regeneration. The aim of this study was to analyze the tissue response of defects created in rabbit skulls to electrical stimulation. Two groups were formed, each with 9 New Zealand rabbits; two 5 mm defects were made, one in each parietal, with one being randomly filled with autogenous bone extracted as particles and the other maintained only with blood clotting. The rabbits were euthanized at 8 weeks and 15 weeks to then study the samples collected histologically. In the 8-week analysis bone formation was observed in the defects in the test and control filled with bone graft, whereas the defects with clotting presented a very early stage of bone formation with abundant connective tissue. At 15 weeks an advanced stage of bone regeneration was identified in the defects with bone graft, whereas no significant differences were found in the electrically stimulated defects. In conclusion, electrical stimulus does not alter the sequence of bone formation; new studies could help establish patterns and influences of the stimulus on bone regeneration.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.33 n.3 20152015-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000300054en10.4067/S0717-95022015000300054
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Electrical stimulus Bone regeneration Bone graft
spellingShingle	Electrical stimulus Bone regeneration Bone graft Silva,C Olate,S Pozzer,L Muñoz,M Cantín,M Uribe,F de Albergaría-Barbosa,J. R Electrical Stimulation in the Bone Repair of Defects Created in Rabbit Skulls
description	Electrical stimulation has been used in different conditions for tissue regeneration. The aim of this study was to analyze the tissue response of defects created in rabbit skulls to electrical stimulation. Two groups were formed, each with 9 New Zealand rabbits; two 5 mm defects were made, one in each parietal, with one being randomly filled with autogenous bone extracted as particles and the other maintained only with blood clotting. The rabbits were euthanized at 8 weeks and 15 weeks to then study the samples collected histologically. In the 8-week analysis bone formation was observed in the defects in the test and control filled with bone graft, whereas the defects with clotting presented a very early stage of bone formation with abundant connective tissue. At 15 weeks an advanced stage of bone regeneration was identified in the defects with bone graft, whereas no significant differences were found in the electrically stimulated defects. In conclusion, electrical stimulus does not alter the sequence of bone formation; new studies could help establish patterns and influences of the stimulus on bone regeneration.
author	Silva,C Olate,S Pozzer,L Muñoz,M Cantín,M Uribe,F de Albergaría-Barbosa,J. R
author_facet	Silva,C Olate,S Pozzer,L Muñoz,M Cantín,M Uribe,F de Albergaría-Barbosa,J. R
author_sort	Silva,C
title	Electrical Stimulation in the Bone Repair of Defects Created in Rabbit Skulls
title_short	Electrical Stimulation in the Bone Repair of Defects Created in Rabbit Skulls
title_full	Electrical Stimulation in the Bone Repair of Defects Created in Rabbit Skulls
title_fullStr	Electrical Stimulation in the Bone Repair of Defects Created in Rabbit Skulls
title_full_unstemmed	Electrical Stimulation in the Bone Repair of Defects Created in Rabbit Skulls
title_sort	electrical stimulation in the bone repair of defects created in rabbit skulls
publisher	Sociedad Chilena de Anatomía
publishDate	2015
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000300054
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Electrical Stimulation in the Bone Repair of Defects Created in Rabbit Skulls

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