Synthesis and Characterization of Calcium Phosphate Compounds with Strontium and Magnesium Ionic Substitutions

Bioceramics offer advantages in the repair and regeneration of hard tissues and are used as bone void fillers and particulate fillers in bone cements with surgical applications. Regeneration and osteosynthesis stimulation via the release of essential ions such as strontium (Sr2+) and magnesium (Mg2+...

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Autores principales:	Rabelo Neto,Jose da Silva, Knopf,Thaiane Balesteri, Fredel,Marcio Celso, Olate,Sergio, de Moraes,Paulo H
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2015
Materias:	Calcium phosphate Biomaterials Bioceramics Hydroxyapatite
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000300061
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spelling	oai:scielo:S0717-950220150003000612015-12-04Synthesis and Characterization of Calcium Phosphate Compounds with Strontium and Magnesium Ionic SubstitutionsRabelo Neto,Jose da SilvaKnopf,Thaiane BalesteriFredel,Marcio CelsoOlate,Sergiode Moraes,Paulo H Calcium phosphate Biomaterials Bioceramics Hydroxyapatite Bioceramics offer advantages in the repair and regeneration of hard tissues and are used as bone void fillers and particulate fillers in bone cements with surgical applications. Regeneration and osteosynthesis stimulation via the release of essential ions such as strontium (Sr2+) and magnesium (Mg2+) is a relatively new field. Therefore, there is great interest in investigating various ionic substitutions on crystallographic structure and characteristics for use in osteoporosis prevent and increase bone formation and decrease bone resorption. In this study, we synthesize calcium phosphate samples with Sr2+ and Mg2+ ionic substitutions. The samples are characterized using X-ray diffraction, Fourier transform infrared spectroscopy, and inductively coupled plasma mass spectroscopy. Hydroxyapatite, beta tricalcium phosphate, and amorphous phases were observed. Depending on the ionic substitution, the crystal size and crystallinity varied from 22 nm to 130 nm and from 84% to 99.6%, respectively. The Ca/P ratio ranged from 0.72 to 1.82. The results demonstrated the effect of Sr2+ and Mg2+ inclusions in calcium phosphate on important parameters used in several bioceramic applications.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.33 n.3 20152015-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000300061en10.4067/S0717-95022015000300061
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Calcium phosphate Biomaterials Bioceramics Hydroxyapatite
spellingShingle	Calcium phosphate Biomaterials Bioceramics Hydroxyapatite Rabelo Neto,Jose da Silva Knopf,Thaiane Balesteri Fredel,Marcio Celso Olate,Sergio de Moraes,Paulo H Synthesis and Characterization of Calcium Phosphate Compounds with Strontium and Magnesium Ionic Substitutions
description	Bioceramics offer advantages in the repair and regeneration of hard tissues and are used as bone void fillers and particulate fillers in bone cements with surgical applications. Regeneration and osteosynthesis stimulation via the release of essential ions such as strontium (Sr2+) and magnesium (Mg2+) is a relatively new field. Therefore, there is great interest in investigating various ionic substitutions on crystallographic structure and characteristics for use in osteoporosis prevent and increase bone formation and decrease bone resorption. In this study, we synthesize calcium phosphate samples with Sr2+ and Mg2+ ionic substitutions. The samples are characterized using X-ray diffraction, Fourier transform infrared spectroscopy, and inductively coupled plasma mass spectroscopy. Hydroxyapatite, beta tricalcium phosphate, and amorphous phases were observed. Depending on the ionic substitution, the crystal size and crystallinity varied from 22 nm to 130 nm and from 84% to 99.6%, respectively. The Ca/P ratio ranged from 0.72 to 1.82. The results demonstrated the effect of Sr2+ and Mg2+ inclusions in calcium phosphate on important parameters used in several bioceramic applications.
author	Rabelo Neto,Jose da Silva Knopf,Thaiane Balesteri Fredel,Marcio Celso Olate,Sergio de Moraes,Paulo H
author_facet	Rabelo Neto,Jose da Silva Knopf,Thaiane Balesteri Fredel,Marcio Celso Olate,Sergio de Moraes,Paulo H
author_sort	Rabelo Neto,Jose da Silva
title	Synthesis and Characterization of Calcium Phosphate Compounds with Strontium and Magnesium Ionic Substitutions
title_short	Synthesis and Characterization of Calcium Phosphate Compounds with Strontium and Magnesium Ionic Substitutions
title_full	Synthesis and Characterization of Calcium Phosphate Compounds with Strontium and Magnesium Ionic Substitutions
title_fullStr	Synthesis and Characterization of Calcium Phosphate Compounds with Strontium and Magnesium Ionic Substitutions
title_full_unstemmed	Synthesis and Characterization of Calcium Phosphate Compounds with Strontium and Magnesium Ionic Substitutions
title_sort	synthesis and characterization of calcium phosphate compounds with strontium and magnesium ionic substitutions
publisher	Sociedad Chilena de Anatomía
publishDate	2015
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000300061
work_keys_str_mv	AT rabelonetojosedasilva synthesisandcharacterizationofcalciumphosphatecompoundswithstrontiumandmagnesiumionicsubstitutions AT knopfthaianebalesteri synthesisandcharacterizationofcalciumphosphatecompoundswithstrontiumandmagnesiumionicsubstitutions AT fredelmarciocelso synthesisandcharacterizationofcalciumphosphatecompoundswithstrontiumandmagnesiumionicsubstitutions AT olatesergio synthesisandcharacterizationofcalciumphosphatecompoundswithstrontiumandmagnesiumionicsubstitutions AT demoraespauloh synthesisandcharacterizationofcalciumphosphatecompoundswithstrontiumandmagnesiumionicsubstitutions
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Synthesis and Characterization of Calcium Phosphate Compounds with Strontium and Magnesium Ionic Substitutions

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