Maternal Malnutrition Diet During Lactation Period Leads to Incomplete Catch-Up Growth in Femur of the Pups at Adulthood

The aim of this study was to evaluate the effects of maternal protein and energy restriction during lactation, analyzing on morphological dimensions whether there was catch-up growth through normative nutrition restored, as well as on mechanical axis of femur of the offspring at adulthood. At partur...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Babinski,Monique S. D, Ramos,Cristiane F, Fernandes,Rodrigo M. P, Cardoso,Gilberto P, Babinski,Marcio A
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2016
Materias:	Rats Femur Undernutrition Growth Morphometry
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000100011
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0717-95022016000100011
record_format	dspace
spelling	oai:scielo:S0717-950220160001000112016-05-02Maternal Malnutrition Diet During Lactation Period Leads to Incomplete Catch-Up Growth in Femur of the Pups at AdulthoodBabinski,Monique S. DRamos,Cristiane FFernandes,Rodrigo M. PCardoso,Gilberto PBabinski,Marcio A Rats Femur Undernutrition Growth Morphometry The aim of this study was to evaluate the effects of maternal protein and energy restriction during lactation, analyzing on morphological dimensions whether there was catch-up growth through normative nutrition restored, as well as on mechanical axis of femur of the offspring at adulthood. At parturition, Wistar rat dams were randomly assigned to the following groups: 1) control group (C) - free access to a standard laboratory diet containing 23 % protein, 2) protein-energy restricted group (PER) - free access to an isoenergetic, protein-restricted diet containing 8 % protein, and 3) energy-restricted group (ER) fed with restricted amounts of a standard laboratory diet. At weaning, all pups were separated of dams and received free access to a standard laboratory diet containing 23 % protein until 180 days, when the rats were anesthetized and sacrificed. The dimensions of excised pup femur were measured directly using pre-established anatomical points. Morphometric analysis of the femur (macroscopic) showed that most of the measurements in the ER and PER groups were significantly lower than in the control group, with the greatest reductions occurring in the PER group and several structural abnormalities. Our results show that protein and energy restriction during lactation leads to an incomplete catch-up growth in adulthood. The femur showed significant reduction in most of the parameters in the two treated groups, particularly the PER group, when compared to the control group.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.34 n.1 20162016-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000100011en10.4067/S0717-95022016000100011
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Rats Femur Undernutrition Growth Morphometry
spellingShingle	Rats Femur Undernutrition Growth Morphometry Babinski,Monique S. D Ramos,Cristiane F Fernandes,Rodrigo M. P Cardoso,Gilberto P Babinski,Marcio A Maternal Malnutrition Diet During Lactation Period Leads to Incomplete Catch-Up Growth in Femur of the Pups at Adulthood
description	The aim of this study was to evaluate the effects of maternal protein and energy restriction during lactation, analyzing on morphological dimensions whether there was catch-up growth through normative nutrition restored, as well as on mechanical axis of femur of the offspring at adulthood. At parturition, Wistar rat dams were randomly assigned to the following groups: 1) control group (C) - free access to a standard laboratory diet containing 23 % protein, 2) protein-energy restricted group (PER) - free access to an isoenergetic, protein-restricted diet containing 8 % protein, and 3) energy-restricted group (ER) fed with restricted amounts of a standard laboratory diet. At weaning, all pups were separated of dams and received free access to a standard laboratory diet containing 23 % protein until 180 days, when the rats were anesthetized and sacrificed. The dimensions of excised pup femur were measured directly using pre-established anatomical points. Morphometric analysis of the femur (macroscopic) showed that most of the measurements in the ER and PER groups were significantly lower than in the control group, with the greatest reductions occurring in the PER group and several structural abnormalities. Our results show that protein and energy restriction during lactation leads to an incomplete catch-up growth in adulthood. The femur showed significant reduction in most of the parameters in the two treated groups, particularly the PER group, when compared to the control group.
author	Babinski,Monique S. D Ramos,Cristiane F Fernandes,Rodrigo M. P Cardoso,Gilberto P Babinski,Marcio A
author_facet	Babinski,Monique S. D Ramos,Cristiane F Fernandes,Rodrigo M. P Cardoso,Gilberto P Babinski,Marcio A
author_sort	Babinski,Monique S. D
title	Maternal Malnutrition Diet During Lactation Period Leads to Incomplete Catch-Up Growth in Femur of the Pups at Adulthood
title_short	Maternal Malnutrition Diet During Lactation Period Leads to Incomplete Catch-Up Growth in Femur of the Pups at Adulthood
title_full	Maternal Malnutrition Diet During Lactation Period Leads to Incomplete Catch-Up Growth in Femur of the Pups at Adulthood
title_fullStr	Maternal Malnutrition Diet During Lactation Period Leads to Incomplete Catch-Up Growth in Femur of the Pups at Adulthood
title_full_unstemmed	Maternal Malnutrition Diet During Lactation Period Leads to Incomplete Catch-Up Growth in Femur of the Pups at Adulthood
title_sort	maternal malnutrition diet during lactation period leads to incomplete catch-up growth in femur of the pups at adulthood
publisher	Sociedad Chilena de Anatomía
publishDate	2016
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000100011
work_keys_str_mv	AT babinskimoniquesd maternalmalnutritiondietduringlactationperiodleadstoincompletecatchupgrowthinfemurofthepupsatadulthood AT ramoscristianef maternalmalnutritiondietduringlactationperiodleadstoincompletecatchupgrowthinfemurofthepupsatadulthood AT fernandesrodrigomp maternalmalnutritiondietduringlactationperiodleadstoincompletecatchupgrowthinfemurofthepupsatadulthood AT cardosogilbertop maternalmalnutritiondietduringlactationperiodleadstoincompletecatchupgrowthinfemurofthepupsatadulthood AT babinskimarcioa maternalmalnutritiondietduringlactationperiodleadstoincompletecatchupgrowthinfemurofthepupsatadulthood
_version_	1718444946673893376

Maternal Malnutrition Diet During Lactation Period Leads to Incomplete Catch-Up Growth in Femur of the Pups at Adulthood

Ejemplares similares