Can the Intermittent Training Generate Alterations on the Liver Tissue of Rats Submitted to a Hyperlipidic Diet?

Studies indicate that increasing physical activity and decreasing levels of fat in the liver help to decrease the risk of morbidity from liver conditions. This study aimed to evaluate the effects of an eight week intermittent training program on the liver tissue of rats subjected to a hyperlipidic d...

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Autores principales:	Magalhães,Alan José Barbosa, Castoldi,Robson Chacon, Camargo,Regina Celi Trindade, Ozaki,Guilherme Akio Tamura, Costalonga,Regiane Rocha, Moreira,Rafael Junges, Seraphim,Patricia Monteiro, Camargo Filho,José Carlos Silva
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2016
Materias:	High fat diet Exercise Hepatocytes
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000100014
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spelling	oai:scielo:S0717-950220160001000142016-05-02Can the Intermittent Training Generate Alterations on the Liver Tissue of Rats Submitted to a Hyperlipidic Diet?Magalhães,Alan José BarbosaCastoldi,Robson ChaconCamargo,Regina Celi TrindadeOzaki,Guilherme Akio TamuraCostalonga,Regiane RochaMoreira,Rafael JungesSeraphim,Patricia MonteiroCamargo Filho,José Carlos Silva High fat diet Exercise Hepatocytes Studies indicate that increasing physical activity and decreasing levels of fat in the liver help to decrease the risk of morbidity from liver conditions. This study aimed to evaluate the effects of an eight week intermittent training program on the liver tissue of rats subjected to a hyperlipidic diet. The study consisted of 30 male Wistar rats, divided into the following groups: Sedentary Control (SC) Exercise Control (EC) (fed on standard feed and water) Sedentary Obese (SO) and Exercise Obese (EO) (fed on bacon, ham, sausage, biscuits, soda and standard feed), which performed intermittent training through electrically stimulated jumps, with three sets of 12 repetitions, three times per week for eight weeks. At the end of the training period, the animals were euthanized, and their livers removed for histological processing and hematoxylin and eosin staining (HE). Soon afterwards, caryometric analysis of the hepatocyte nuclei was performed. From the presented results it can be seen that the hepatocyte nuclei of the obese animals were smaller in relation to those of the control animals, therefore, exercise combined with an appropriate diet proved to be efficient in not causing alterations in the hepatocyte nuclei, conserving normal cell function and reducing the chances of the appearance of tissue damage. Furthermore, exercise in isolation cannot be considered a protective factor against the alteration of the liver cells.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.34 n.1 20162016-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000100014en10.4067/S0717-95022016000100014
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	High fat diet Exercise Hepatocytes
spellingShingle	High fat diet Exercise Hepatocytes Magalhães,Alan José Barbosa Castoldi,Robson Chacon Camargo,Regina Celi Trindade Ozaki,Guilherme Akio Tamura Costalonga,Regiane Rocha Moreira,Rafael Junges Seraphim,Patricia Monteiro Camargo Filho,José Carlos Silva Can the Intermittent Training Generate Alterations on the Liver Tissue of Rats Submitted to a Hyperlipidic Diet?
description	Studies indicate that increasing physical activity and decreasing levels of fat in the liver help to decrease the risk of morbidity from liver conditions. This study aimed to evaluate the effects of an eight week intermittent training program on the liver tissue of rats subjected to a hyperlipidic diet. The study consisted of 30 male Wistar rats, divided into the following groups: Sedentary Control (SC) Exercise Control (EC) (fed on standard feed and water) Sedentary Obese (SO) and Exercise Obese (EO) (fed on bacon, ham, sausage, biscuits, soda and standard feed), which performed intermittent training through electrically stimulated jumps, with three sets of 12 repetitions, three times per week for eight weeks. At the end of the training period, the animals were euthanized, and their livers removed for histological processing and hematoxylin and eosin staining (HE). Soon afterwards, caryometric analysis of the hepatocyte nuclei was performed. From the presented results it can be seen that the hepatocyte nuclei of the obese animals were smaller in relation to those of the control animals, therefore, exercise combined with an appropriate diet proved to be efficient in not causing alterations in the hepatocyte nuclei, conserving normal cell function and reducing the chances of the appearance of tissue damage. Furthermore, exercise in isolation cannot be considered a protective factor against the alteration of the liver cells.
author	Magalhães,Alan José Barbosa Castoldi,Robson Chacon Camargo,Regina Celi Trindade Ozaki,Guilherme Akio Tamura Costalonga,Regiane Rocha Moreira,Rafael Junges Seraphim,Patricia Monteiro Camargo Filho,José Carlos Silva
author_facet	Magalhães,Alan José Barbosa Castoldi,Robson Chacon Camargo,Regina Celi Trindade Ozaki,Guilherme Akio Tamura Costalonga,Regiane Rocha Moreira,Rafael Junges Seraphim,Patricia Monteiro Camargo Filho,José Carlos Silva
author_sort	Magalhães,Alan José Barbosa
title	Can the Intermittent Training Generate Alterations on the Liver Tissue of Rats Submitted to a Hyperlipidic Diet?
title_short	Can the Intermittent Training Generate Alterations on the Liver Tissue of Rats Submitted to a Hyperlipidic Diet?
title_full	Can the Intermittent Training Generate Alterations on the Liver Tissue of Rats Submitted to a Hyperlipidic Diet?
title_fullStr	Can the Intermittent Training Generate Alterations on the Liver Tissue of Rats Submitted to a Hyperlipidic Diet?
title_full_unstemmed	Can the Intermittent Training Generate Alterations on the Liver Tissue of Rats Submitted to a Hyperlipidic Diet?
title_sort	can the intermittent training generate alterations on the liver tissue of rats submitted to a hyperlipidic diet?
publisher	Sociedad Chilena de Anatomía
publishDate	2016
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000100014
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Can the Intermittent Training Generate Alterations on the Liver Tissue of Rats Submitted to a Hyperlipidic Diet?

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