Characterization of Tympanic Cavity Volume in Newborns using Computerized Tomography Scanning

This study reports tympanic cavity (TC) volume in newborns, which was missing in the literature. Ex vivo histology and computerized tomography (CT) scans were performed on temporal bone and data were analyzed in part using software developed in house. CT images with a slice thickness of 0.5 mm were...

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Autores principales:	Acer,Niyazi, Unur,Erdogan, Sönmez,M. Fatih, Zararsiz,Gökmen, Arslan,Ayla, Sagiroglu,Ayse, Ertekin,Tolga, Erkan,Mustafa, Coskun,Abdulhakim, Bilgen,Mehmet
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2016
Materias:	Computerized tomography Tympanic cavity Tympanic cavity volume Similarity index
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000100027
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spelling	oai:scielo:S0717-950220160001000272016-05-02Characterization of Tympanic Cavity Volume in Newborns using Computerized Tomography ScanningAcer,NiyaziUnur,ErdoganSönmez,M. FatihZararsiz,GökmenArslan,AylaSagiroglu,AyseErtekin,TolgaErkan,MustafaCoskun,AbdulhakimBilgen,Mehmet Computerized tomography Tympanic cavity Tympanic cavity volume Similarity index This study reports tympanic cavity (TC) volume in newborns, which was missing in the literature. Ex vivo histology and computerized tomography (CT) scans were performed on temporal bone and data were analyzed in part using software developed in house. CT images with a slice thickness of 0.5 mm were obtained from 5 newborn cadavers and analyzed independently by two expert researchers. The border of the TC was delineated manually and measurement of area of interest was calculated on masked images. Then, the area measurements from all sections were added to estimate the total volume. The agreements between the histological and CT findings were then compared for accuracy, repeatability and reliability. The Dice and Jaccard similarity coefficient measures were used as a statistical validation metric to evaluate the assessor's performance in manual volume segmentation. Good assessor agreement was observed with average Dice values above 0.8 indicating that consistent and reliable volume measurements were feasible. The proposed protocol was shown to be accurate in calculating the TC volume, and thus can be used for computer-assisted presurgical planning or for diagnosing structural alterations in TC.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.34 n.1 20162016-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000100027en10.4067/S0717-95022016000100027
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Computerized tomography Tympanic cavity Tympanic cavity volume Similarity index
spellingShingle	Computerized tomography Tympanic cavity Tympanic cavity volume Similarity index Acer,Niyazi Unur,Erdogan Sönmez,M. Fatih Zararsiz,Gökmen Arslan,Ayla Sagiroglu,Ayse Ertekin,Tolga Erkan,Mustafa Coskun,Abdulhakim Bilgen,Mehmet Characterization of Tympanic Cavity Volume in Newborns using Computerized Tomography Scanning
description	This study reports tympanic cavity (TC) volume in newborns, which was missing in the literature. Ex vivo histology and computerized tomography (CT) scans were performed on temporal bone and data were analyzed in part using software developed in house. CT images with a slice thickness of 0.5 mm were obtained from 5 newborn cadavers and analyzed independently by two expert researchers. The border of the TC was delineated manually and measurement of area of interest was calculated on masked images. Then, the area measurements from all sections were added to estimate the total volume. The agreements between the histological and CT findings were then compared for accuracy, repeatability and reliability. The Dice and Jaccard similarity coefficient measures were used as a statistical validation metric to evaluate the assessor's performance in manual volume segmentation. Good assessor agreement was observed with average Dice values above 0.8 indicating that consistent and reliable volume measurements were feasible. The proposed protocol was shown to be accurate in calculating the TC volume, and thus can be used for computer-assisted presurgical planning or for diagnosing structural alterations in TC.
author	Acer,Niyazi Unur,Erdogan Sönmez,M. Fatih Zararsiz,Gökmen Arslan,Ayla Sagiroglu,Ayse Ertekin,Tolga Erkan,Mustafa Coskun,Abdulhakim Bilgen,Mehmet
author_facet	Acer,Niyazi Unur,Erdogan Sönmez,M. Fatih Zararsiz,Gökmen Arslan,Ayla Sagiroglu,Ayse Ertekin,Tolga Erkan,Mustafa Coskun,Abdulhakim Bilgen,Mehmet
author_sort	Acer,Niyazi
title	Characterization of Tympanic Cavity Volume in Newborns using Computerized Tomography Scanning
title_short	Characterization of Tympanic Cavity Volume in Newborns using Computerized Tomography Scanning
title_full	Characterization of Tympanic Cavity Volume in Newborns using Computerized Tomography Scanning
title_fullStr	Characterization of Tympanic Cavity Volume in Newborns using Computerized Tomography Scanning
title_full_unstemmed	Characterization of Tympanic Cavity Volume in Newborns using Computerized Tomography Scanning
title_sort	characterization of tympanic cavity volume in newborns using computerized tomography scanning
publisher	Sociedad Chilena de Anatomía
publishDate	2016
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000100027
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Characterization of Tympanic Cavity Volume in Newborns using Computerized Tomography Scanning

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