Effects of Xylene on Respiratory Mucosa in Rats

In this study we examined the effects histopathologic and immunohistochemical of xylene inhalation in rats by using light microscopy. Adult wistar albino rats were used in this study. Eight rats were in control group and 8 rats were in the experimental group. The experimental group was exposed to 30...

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Autores principales: Arslan,Eda, Samanci,Baver, Samanci,Bölükbasi Seyla, Özevren,Hüseyin, Deveci,E
Lenguaje:English
Publicado: Sociedad Chilena de Anatomía 2016
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000300019
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spelling oai:scielo:S0717-950220160003000192016-11-17Effects of Xylene on Respiratory Mucosa in RatsArslan,EdaSamanci,BaverSamanci,Bölükbasi SeylaÖzevren,HüseyinDeveci,E Xylene Vascular endothelial growth factor E-Cadherin Respiratory mucosa In this study we examined the effects histopathologic and immunohistochemical of xylene inhalation in rats by using light microscopy. Adult wistar albino rats were used in this study. Eight rats were in control group and 8 rats were in the experimental group. The experimental group was exposed to 300 ppm formaldehyde 3­5 min/day, 5 days/week for 8 weeks. The lining epithelium of respiratory mucosa showed a loss of ciliated cells with metaplasia of goblet cells, hyperplasia of squamous cells and edema, inflamation in sub epithelial area). In the group treated xylene. Disruption of cell-cell contact was observed. Weak expression of E-cadherin was observed between cells. The vascular endothelium of capillaries and venoles showed intense immunostaining for VEGF.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.34 n.3 20162016-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000300019en10.4067/S0717-95022016000300019
institution Scielo Chile
collection Scielo Chile
language English
topic Xylene
Vascular endothelial growth factor
E-Cadherin
Respiratory mucosa
spellingShingle Xylene
Vascular endothelial growth factor
E-Cadherin
Respiratory mucosa
Arslan,Eda
Samanci,Baver
Samanci,Bölükbasi Seyla
Özevren,Hüseyin
Deveci,E
Effects of Xylene on Respiratory Mucosa in Rats
description In this study we examined the effects histopathologic and immunohistochemical of xylene inhalation in rats by using light microscopy. Adult wistar albino rats were used in this study. Eight rats were in control group and 8 rats were in the experimental group. The experimental group was exposed to 300 ppm formaldehyde 3­5 min/day, 5 days/week for 8 weeks. The lining epithelium of respiratory mucosa showed a loss of ciliated cells with metaplasia of goblet cells, hyperplasia of squamous cells and edema, inflamation in sub epithelial area). In the group treated xylene. Disruption of cell-cell contact was observed. Weak expression of E-cadherin was observed between cells. The vascular endothelium of capillaries and venoles showed intense immunostaining for VEGF.
author Arslan,Eda
Samanci,Baver
Samanci,Bölükbasi Seyla
Özevren,Hüseyin
Deveci,E
author_facet Arslan,Eda
Samanci,Baver
Samanci,Bölükbasi Seyla
Özevren,Hüseyin
Deveci,E
author_sort Arslan,Eda
title Effects of Xylene on Respiratory Mucosa in Rats
title_short Effects of Xylene on Respiratory Mucosa in Rats
title_full Effects of Xylene on Respiratory Mucosa in Rats
title_fullStr Effects of Xylene on Respiratory Mucosa in Rats
title_full_unstemmed Effects of Xylene on Respiratory Mucosa in Rats
title_sort effects of xylene on respiratory mucosa in rats
publisher Sociedad Chilena de Anatomía
publishDate 2016
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000300019
work_keys_str_mv AT arslaneda effectsofxyleneonrespiratorymucosainrats
AT samancibaver effectsofxyleneonrespiratorymucosainrats
AT samancibolukbasiseyla effectsofxyleneonrespiratorymucosainrats
AT ozevrenhuseyin effectsofxyleneonrespiratorymucosainrats
AT devecie effectsofxyleneonrespiratorymucosainrats
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