Age-Related Changes in the Expression of ICAM-1 in the Aorta of Wistar Albino Rats

ICAM-1 which is expressed by endothelial cells and leukocytes are observed as first markers in diseases such as transplant rejection, diabetes and atherosclerosis and in infections caused by various pathogens. In the present study, it is aimed to reveal the age-related changes in the expression of I...

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Autores principales:	Ketani,Sennur, Karakoç,Zelal, Ketani,M. Aydin, Kilinç,Mehmet
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2016
Materias:	ICAM-1 Rat Aortic endothelium Age
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000400049
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spelling	oai:scielo:S0717-950220160004000492017-02-01Age-Related Changes in the Expression of ICAM-1 in the Aorta of Wistar Albino RatsKetani,SennurKarakoç,ZelalKetani,M. AydinKilinç,Mehmet ICAM-1 Rat Aortic endothelium Age ICAM-1 which is expressed by endothelial cells and leukocytes are observed as first markers in diseases such as transplant rejection, diabetes and atherosclerosis and in infections caused by various pathogens. In the present study, it is aimed to reveal the age-related changes in the expression of ICAM-1 on rats. Therefore, a total of 30 albino rats were taken at the age of 6, 18 and 24 months without gender discrimination. Rats were fed with standard pellet feed during the study. Afterwards, rats were sacrificed and tissue samples were collected from their rats, and the samples were evaluated under the light microscope by staining with immnunohistochemical method. It was determined that the expression of both aortic endothelial cells and endothelial cells in the media layer had been significantly increased based on the age.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.34 n.4 20162016-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000400049en10.4067/S0717-95022016000400049
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	ICAM-1 Rat Aortic endothelium Age
spellingShingle	ICAM-1 Rat Aortic endothelium Age Ketani,Sennur Karakoç,Zelal Ketani,M. Aydin Kilinç,Mehmet Age-Related Changes in the Expression of ICAM-1 in the Aorta of Wistar Albino Rats
description	ICAM-1 which is expressed by endothelial cells and leukocytes are observed as first markers in diseases such as transplant rejection, diabetes and atherosclerosis and in infections caused by various pathogens. In the present study, it is aimed to reveal the age-related changes in the expression of ICAM-1 on rats. Therefore, a total of 30 albino rats were taken at the age of 6, 18 and 24 months without gender discrimination. Rats were fed with standard pellet feed during the study. Afterwards, rats were sacrificed and tissue samples were collected from their rats, and the samples were evaluated under the light microscope by staining with immnunohistochemical method. It was determined that the expression of both aortic endothelial cells and endothelial cells in the media layer had been significantly increased based on the age.
author	Ketani,Sennur Karakoç,Zelal Ketani,M. Aydin Kilinç,Mehmet
author_facet	Ketani,Sennur Karakoç,Zelal Ketani,M. Aydin Kilinç,Mehmet
author_sort	Ketani,Sennur
title	Age-Related Changes in the Expression of ICAM-1 in the Aorta of Wistar Albino Rats
title_short	Age-Related Changes in the Expression of ICAM-1 in the Aorta of Wistar Albino Rats
title_full	Age-Related Changes in the Expression of ICAM-1 in the Aorta of Wistar Albino Rats
title_fullStr	Age-Related Changes in the Expression of ICAM-1 in the Aorta of Wistar Albino Rats
title_full_unstemmed	Age-Related Changes in the Expression of ICAM-1 in the Aorta of Wistar Albino Rats
title_sort	age-related changes in the expression of icam-1 in the aorta of wistar albino rats
publisher	Sociedad Chilena de Anatomía
publishDate	2016
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000400049
work_keys_str_mv	AT ketanisennur agerelatedchangesintheexpressionoficam1intheaortaofwistaralbinorats AT karakoczelal agerelatedchangesintheexpressionoficam1intheaortaofwistaralbinorats AT ketanimaydin agerelatedchangesintheexpressionoficam1intheaortaofwistaralbinorats AT kilincmehmet agerelatedchangesintheexpressionoficam1intheaortaofwistaralbinorats
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Age-Related Changes in the Expression of ICAM-1 in the Aorta of Wistar Albino Rats

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