The Impact of Proximol (Cymbopogon proximus) Intakeon Pregnant Albino Ratsand their Fetuses During Gestation Period

Halphabarol, the active principle of Proximol, is the most potent of the four antispasmodics present in the national desert weed Cymbopogon proximus or ''Halfa Bar''. Halphabarol is of great value for the management of renal colic and in the expulsion of ureteric calculi as it ca...

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Autores principales:	Abdelrahman,Heba A, Omar,Amel R, Salah EL-Din,Eman Y
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2017
Materias:	Cymbopogon proximus Halfa Bar Malformation
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000200019
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spelling	oai:scielo:S0717-950220170002000192017-08-07The Impact of Proximol (Cymbopogon proximus) Intakeon Pregnant Albino Ratsand their Fetuses During Gestation PeriodAbdelrahman,Heba AOmar,Amel RSalah EL-Din,Eman Y Cymbopogon proximus Halfa Bar Malformation Halphabarol, the active principle of Proximol, is the most potent of the four antispasmodics present in the national desert weed Cymbopogon proximus or ''Halfa Bar''. Halphabarol is of great value for the management of renal colic and in the expulsion of ureteric calculi as it causes dilation of the ureter below the site of calculus while active propulsion is maintained. Evaluation the congenital malformation of proximol in pregnant albino rats during gestation period. The virgin female rats were mated with male rats and the pregnant rats were orally administered a human equivalent dose (0.05 mg/kg) of Proximol from 5th-20th gestation day. At day 20 of pregnancy, all rats were anesthetized to obtained maternal and fetal data. The treatment group displayed some disorders, which can be summarized as growth retardation, external anomalies, embryonic resorption, and skeletal malformation. We concluded that the oral administration of Proximol resulted in embryonic abnormalities and skeletal malformations.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.35 n.2 20172017-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000200019en10.4067/S0717-95022017000200019
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Cymbopogon proximus Halfa Bar Malformation
spellingShingle	Cymbopogon proximus Halfa Bar Malformation Abdelrahman,Heba A Omar,Amel R Salah EL-Din,Eman Y The Impact of Proximol (Cymbopogon proximus) Intakeon Pregnant Albino Ratsand their Fetuses During Gestation Period
description	Halphabarol, the active principle of Proximol, is the most potent of the four antispasmodics present in the national desert weed Cymbopogon proximus or ''Halfa Bar''. Halphabarol is of great value for the management of renal colic and in the expulsion of ureteric calculi as it causes dilation of the ureter below the site of calculus while active propulsion is maintained. Evaluation the congenital malformation of proximol in pregnant albino rats during gestation period. The virgin female rats were mated with male rats and the pregnant rats were orally administered a human equivalent dose (0.05 mg/kg) of Proximol from 5th-20th gestation day. At day 20 of pregnancy, all rats were anesthetized to obtained maternal and fetal data. The treatment group displayed some disorders, which can be summarized as growth retardation, external anomalies, embryonic resorption, and skeletal malformation. We concluded that the oral administration of Proximol resulted in embryonic abnormalities and skeletal malformations.
author	Abdelrahman,Heba A Omar,Amel R Salah EL-Din,Eman Y
author_facet	Abdelrahman,Heba A Omar,Amel R Salah EL-Din,Eman Y
author_sort	Abdelrahman,Heba A
title	The Impact of Proximol (Cymbopogon proximus) Intakeon Pregnant Albino Ratsand their Fetuses During Gestation Period
title_short	The Impact of Proximol (Cymbopogon proximus) Intakeon Pregnant Albino Ratsand their Fetuses During Gestation Period
title_full	The Impact of Proximol (Cymbopogon proximus) Intakeon Pregnant Albino Ratsand their Fetuses During Gestation Period
title_fullStr	The Impact of Proximol (Cymbopogon proximus) Intakeon Pregnant Albino Ratsand their Fetuses During Gestation Period
title_full_unstemmed	The Impact of Proximol (Cymbopogon proximus) Intakeon Pregnant Albino Ratsand their Fetuses During Gestation Period
title_sort	impact of proximol (cymbopogon proximus) intakeon pregnant albino ratsand their fetuses during gestation period
publisher	Sociedad Chilena de Anatomía
publishDate	2017
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000200019
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The Impact of Proximol (Cymbopogon proximus) Intakeon Pregnant Albino Ratsand their Fetuses During Gestation Period

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