Effects of Potentilla fulgens on the Changes Made in the Retinal Damage Induced by Traumatic Head Injury

Traumatic head injury is a leading cause of mortality and morbidity. As a result of head trauma occurring in the retina of the various biochemical, histological and immunohistochemical effects were investigated. SpragueDawley rats were subjected to traumatic brain injury with a weight-drop device u...

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Autores principales:	Hüseyin,Özevren, Engin,Deveci
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2017
Materias:	Traumatic injury Retina Potentilla fulgens Rat
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000300007
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spelling	oai:scielo:S0717-950220170003000072017-11-20Effects of Potentilla fulgens on the Changes Made in the Retinal Damage Induced by Traumatic Head InjuryHüseyin,ÖzevrenEngin,Deveci Traumatic injury Retina Potentilla fulgens Rat Traumatic head injury is a leading cause of mortality and morbidity. As a result of head trauma occurring in the retina of the various biochemical, histological and immunohistochemical effects were investigated. SpragueDawley rats were subjected to traumatic brain injury with a weight-drop device using 300 g-1 m weightheight impact. Twenty one rats were divided into three groups, as group 1 (vehicle-treated control), group 2 (vehicle-treated trauma) group 3 trauma + Potentilla fulgens ( P. Fulgens) 400 mg/kg/day, i.p.). Distilled water was used as vehicle. All rats were decapitated 5 days after the induction of trauma, and the protective effects of P. Fulgens were evaluated by histological, immunohistochemical and biochemical analyses. Although further studies are necessary to evaluate the time-and dose-dependent neuroprotective effects of P. Fulgens. Depending on whether trauma inhibits apoptosis of photoreceptor cells, ganglion cells, it is thought that the the support against the degeneration of neural connections can be considered. This study indicates that P.Fulgens is potentially useful for the treatment of eye disorders induced by traumatic brain injury.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.35 n.3 20172017-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000300007en10.4067/S0717-95022017000300007
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Traumatic injury Retina Potentilla fulgens Rat
spellingShingle	Traumatic injury Retina Potentilla fulgens Rat Hüseyin,Özevren Engin,Deveci Effects of Potentilla fulgens on the Changes Made in the Retinal Damage Induced by Traumatic Head Injury
description	Traumatic head injury is a leading cause of mortality and morbidity. As a result of head trauma occurring in the retina of the various biochemical, histological and immunohistochemical effects were investigated. SpragueDawley rats were subjected to traumatic brain injury with a weight-drop device using 300 g-1 m weightheight impact. Twenty one rats were divided into three groups, as group 1 (vehicle-treated control), group 2 (vehicle-treated trauma) group 3 trauma + Potentilla fulgens ( P. Fulgens) 400 mg/kg/day, i.p.). Distilled water was used as vehicle. All rats were decapitated 5 days after the induction of trauma, and the protective effects of P. Fulgens were evaluated by histological, immunohistochemical and biochemical analyses. Although further studies are necessary to evaluate the time-and dose-dependent neuroprotective effects of P. Fulgens. Depending on whether trauma inhibits apoptosis of photoreceptor cells, ganglion cells, it is thought that the the support against the degeneration of neural connections can be considered. This study indicates that P.Fulgens is potentially useful for the treatment of eye disorders induced by traumatic brain injury.
author	Hüseyin,Özevren Engin,Deveci
author_facet	Hüseyin,Özevren Engin,Deveci
author_sort	Hüseyin,Özevren
title	Effects of Potentilla fulgens on the Changes Made in the Retinal Damage Induced by Traumatic Head Injury
title_short	Effects of Potentilla fulgens on the Changes Made in the Retinal Damage Induced by Traumatic Head Injury
title_full	Effects of Potentilla fulgens on the Changes Made in the Retinal Damage Induced by Traumatic Head Injury
title_fullStr	Effects of Potentilla fulgens on the Changes Made in the Retinal Damage Induced by Traumatic Head Injury
title_full_unstemmed	Effects of Potentilla fulgens on the Changes Made in the Retinal Damage Induced by Traumatic Head Injury
title_sort	effects of potentilla fulgens on the changes made in the retinal damage induced by traumatic head injury
publisher	Sociedad Chilena de Anatomía
publishDate	2017
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000300007
work_keys_str_mv	AT huseyinozevren effectsofpotentillafulgensonthechangesmadeintheretinaldamageinducedbytraumaticheadinjury AT engindeveci effectsofpotentillafulgensonthechangesmadeintheretinaldamageinducedbytraumaticheadinjury
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Effects of Potentilla fulgens on the Changes Made in the Retinal Damage Induced by Traumatic Head Injury

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