The Effect of Low Protein on Colonic Mucosal Barrier in Pigs
Reducing nitrogen nutrients concentration in dairy food is economic for pig industry. Here, we used finishing pig as model to investigate the effect on colon mucosal barrier and nutrients absorption after reducing crude protein (CP) in dietary from 16 % to 13 %. The results showed that crypt depth,...
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Sociedad Chilena de Anatomía
2017
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oai:scielo:S0717-950220170003000132017-11-20The Effect of Low Protein on Colonic Mucosal Barrier in PigsHou,QihangXia,MiHu,WiweiYu,QinghuaZhang,Bingkun Amino acid transporter Pig Colon Goblet cell Tight junction Reducing nitrogen nutrients concentration in dairy food is economic for pig industry. Here, we used finishing pig as model to investigate the effect on colon mucosal barrier and nutrients absorption after reducing crude protein (CP) in dietary from 16 % to 13 %. The results showed that crypt depth, cells, claudin-1 and E-cadherin expression level will not be changed, which implied the integrity of colon mucosal structure. Furthermore, the expressions of ASCT1, EAAT3 and SGLT1 in colon were also maintained at normal levels in 13 % CP dietary. Interestingly, the CAT1 and GLUT2 expression were increased significantly after reducing CP level to 13 %, which might be attributed to the compensatory nutrients absorption. This study implied that 13 % CP was sufficient to maintain normal colon structure and will not change intestinal morphology, which provided a basis for an ideal economic protein feed formula.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.35 n.3 20172017-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000300013en10.4067/S0717-95022017000300013 |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
English |
| topic |
Amino acid transporter Pig Colon Goblet cell Tight junction |
| spellingShingle |
Amino acid transporter Pig Colon Goblet cell Tight junction Hou,Qihang Xia,Mi Hu,Wiwei Yu,Qinghua Zhang,Bingkun The Effect of Low Protein on Colonic Mucosal Barrier in Pigs |
| description |
Reducing nitrogen nutrients concentration in dairy food is economic for pig industry. Here, we used finishing pig as model to investigate the effect on colon mucosal barrier and nutrients absorption after reducing crude protein (CP) in dietary from 16 % to 13 %. The results showed that crypt depth, cells, claudin-1 and E-cadherin expression level will not be changed, which implied the integrity of colon mucosal structure. Furthermore, the expressions of ASCT1, EAAT3 and SGLT1 in colon were also maintained at normal levels in 13 % CP dietary. Interestingly, the CAT1 and GLUT2 expression were increased significantly after reducing CP level to 13 %, which might be attributed to the compensatory nutrients absorption. This study implied that 13 % CP was sufficient to maintain normal colon structure and will not change intestinal morphology, which provided a basis for an ideal economic protein feed formula. |
| author |
Hou,Qihang Xia,Mi Hu,Wiwei Yu,Qinghua Zhang,Bingkun |
| author_facet |
Hou,Qihang Xia,Mi Hu,Wiwei Yu,Qinghua Zhang,Bingkun |
| author_sort |
Hou,Qihang |
| title |
The Effect of Low Protein on Colonic Mucosal Barrier in Pigs |
| title_short |
The Effect of Low Protein on Colonic Mucosal Barrier in Pigs |
| title_full |
The Effect of Low Protein on Colonic Mucosal Barrier in Pigs |
| title_fullStr |
The Effect of Low Protein on Colonic Mucosal Barrier in Pigs |
| title_full_unstemmed |
The Effect of Low Protein on Colonic Mucosal Barrier in Pigs |
| title_sort |
effect of low protein on colonic mucosal barrier in pigs |
| publisher |
Sociedad Chilena de Anatomía |
| publishDate |
2017 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000300013 |
| work_keys_str_mv |
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| _version_ |
1718445011258834944 |