Protective Effects of Ganoderma lucidum on the Changes Made in the Retinal Damage Induced by Traumatic Head Injury

Head trauma affects the optic nerve visual function and visual acuity. As a result of head trauma occurring in the retina of the various biochemical, histological and immunohistochemical effects were investigated. The protective effect of Ganoderma lucidum was evaluated on the damage to the retina o...

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Autores principales:	Özevren,Hüseyin, Deveci,Engin
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2017
Materias:	Head trauma Retina Ganoderma lucidum Rat
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000300040
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spelling	oai:scielo:S0717-950220170003000402017-11-20Protective Effects of Ganoderma lucidum on the Changes Made in the Retinal Damage Induced by Traumatic Head InjuryÖzevren,HüseyinDeveci,Engin Head trauma Retina Ganoderma lucidum Rat Head trauma affects the optic nerve visual function and visual acuity. As a result of head trauma occurring in the retina of the various biochemical, histological and immunohistochemical effects were investigated. The protective effect of Ganoderma lucidum was evaluated on the damage to the retina of the rats. Sprague-Dawley rats were subjected to traumatic brain injury with a weight-drop device using 300 g-1 m weight-height impact. Thirty rats were divided into three groups as group 1 control, 2 group trauma, 3 group trauma+Gonoderma lucidum (20 mL/kg per day via gastric gavage) Ganoderma lucidum was administered for 7 days after trauma.All rats were decapitated 5 days after the induction of trauma, and the protective effects of Ganoderma lucidum in retina were evaluated by histological, immunohistochemical and biochemical analyses. The antioxidant effect of Ganoderma lucidum on the cellular degeneration extracellular matrix and retinal barrier in retina after head trauma was investigated.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.35 n.3 20172017-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000300040en10.4067/S0717-95022017000300040
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Head trauma Retina Ganoderma lucidum Rat
spellingShingle	Head trauma Retina Ganoderma lucidum Rat Özevren,Hüseyin Deveci,Engin Protective Effects of Ganoderma lucidum on the Changes Made in the Retinal Damage Induced by Traumatic Head Injury
description	Head trauma affects the optic nerve visual function and visual acuity. As a result of head trauma occurring in the retina of the various biochemical, histological and immunohistochemical effects were investigated. The protective effect of Ganoderma lucidum was evaluated on the damage to the retina of the rats. Sprague-Dawley rats were subjected to traumatic brain injury with a weight-drop device using 300 g-1 m weight-height impact. Thirty rats were divided into three groups as group 1 control, 2 group trauma, 3 group trauma+Gonoderma lucidum (20 mL/kg per day via gastric gavage) Ganoderma lucidum was administered for 7 days after trauma.All rats were decapitated 5 days after the induction of trauma, and the protective effects of Ganoderma lucidum in retina were evaluated by histological, immunohistochemical and biochemical analyses. The antioxidant effect of Ganoderma lucidum on the cellular degeneration extracellular matrix and retinal barrier in retina after head trauma was investigated.
author	Özevren,Hüseyin Deveci,Engin
author_facet	Özevren,Hüseyin Deveci,Engin
author_sort	Özevren,Hüseyin
title	Protective Effects of Ganoderma lucidum on the Changes Made in the Retinal Damage Induced by Traumatic Head Injury
title_short	Protective Effects of Ganoderma lucidum on the Changes Made in the Retinal Damage Induced by Traumatic Head Injury
title_full	Protective Effects of Ganoderma lucidum on the Changes Made in the Retinal Damage Induced by Traumatic Head Injury
title_fullStr	Protective Effects of Ganoderma lucidum on the Changes Made in the Retinal Damage Induced by Traumatic Head Injury
title_full_unstemmed	Protective Effects of Ganoderma lucidum on the Changes Made in the Retinal Damage Induced by Traumatic Head Injury
title_sort	protective effects of ganoderma lucidum on the changes made in the retinal damage induced by traumatic head injury
publisher	Sociedad Chilena de Anatomía
publishDate	2017
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000300040
work_keys_str_mv	AT ozevrenhuseyin protectiveeffectsofganodermalucidumonthechangesmadeintheretinaldamageinducedbytraumaticheadinjury AT deveciengin protectiveeffectsofganodermalucidumonthechangesmadeintheretinaldamageinducedbytraumaticheadinjury
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Protective Effects of Ganoderma lucidum on the Changes Made in the Retinal Damage Induced by Traumatic Head Injury

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