Development of a Rat Model of Knee Osteoarthritis by a Combination of Monoiodoacetate and Streptozotocin

SUMMARY: Osteoarthritis (OA) caused by ageing joints or as a secondary complication of diabetes is a common health problem. We sought to develop an animal model of OA induced by a combination of the chondrocyte glycolytic inhibitor mono-iodoacetate (MIA) and streptozotocin (STZ), the agent that indu...

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Main Authors: Heidar,El Hassan A., Al-Ani,Bahjat, Haidara,Mohamed A, Al-Faya,Fareed F, Al-Humayed,Suliman, Eid,Refaat A, Hassan,Waleed N.
Language:English
Published: Sociedad Chilena de Anatomía 2017
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Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000401383
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