Investigation of Allium sativum’s Protective Effect on Ovarian Reserve in an Experimental Ovarian Injury Model
SUMMARY: We aimed to evaluate the effects of detorsion and Allium sativum (garlic oil) treatment on the ovarian reserve in an ovarian torsion model. Ovarian torsion may lead to loss of ovarian tissue and infertility. It is an experimental rat study that was carried out on 16 sets of ovaries each, on...
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| Lenguaje: | English |
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Sociedad Chilena de Anatomía
2018
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oai:scielo:S0717-950220180002003952019-09-16Investigation of Allium sativum’s Protective Effect on Ovarian Reserve in an Experimental Ovarian Injury ModelGüney,GürhanKaya,CihanYildirim,SerkanOto,GökhanEkin,SuatÖzdemir,Hülya Anti-Müllerian hormone Detorsion Allium sativum Ovarian reserve Oxidative stress SUMMARY: We aimed to evaluate the effects of detorsion and Allium sativum (garlic oil) treatment on the ovarian reserve in an ovarian torsion model. Ovarian torsion may lead to loss of ovarian tissue and infertility. It is an experimental rat study that was carried out on 16 sets of ovaries each, one for treatment group and a control group. In the control group, the procedure involved only the surgically opening and closing the abdomen. Bilateral adnexal torsion/detorsion was performed after a 3-hour ischemia period for the detorsion-only group. The detorsion + Allium sativum group received a 5 ml/kg dose of Allium sativum intraperitoneally, 2 hours before surgery. After the second surgery, removed ovarian samples were evaluated for follicle counts, damage scores and other parameters. Primordial, preantral, small antral and large antral follicle counts were significantly higher in the detorsion + Allium sativum group. Degeneration, congestion, hemorrhage ,inflammation and total damage scores were significantly elevated in the detorsion only group compared to those for the detorsion + Allium sativum group. Finally, there was a significant correlation between AMH alterations and postoperative, preantral follicle count (p<0.05). As a conclusion detorsion + Allium sativum treatment may be effective in protecting the ovarian reserve after torsion.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.36 n.2 20182018-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022018000200395en10.4067/S0717-95022018000200395 |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
English |
| topic |
Anti-Müllerian hormone Detorsion Allium sativum Ovarian reserve Oxidative stress |
| spellingShingle |
Anti-Müllerian hormone Detorsion Allium sativum Ovarian reserve Oxidative stress Güney,Gürhan Kaya,Cihan Yildirim,Serkan Oto,Gökhan Ekin,Suat Özdemir,Hülya Investigation of Allium sativum’s Protective Effect on Ovarian Reserve in an Experimental Ovarian Injury Model |
| description |
SUMMARY: We aimed to evaluate the effects of detorsion and Allium sativum (garlic oil) treatment on the ovarian reserve in an ovarian torsion model. Ovarian torsion may lead to loss of ovarian tissue and infertility. It is an experimental rat study that was carried out on 16 sets of ovaries each, one for treatment group and a control group. In the control group, the procedure involved only the surgically opening and closing the abdomen. Bilateral adnexal torsion/detorsion was performed after a 3-hour ischemia period for the detorsion-only group. The detorsion + Allium sativum group received a 5 ml/kg dose of Allium sativum intraperitoneally, 2 hours before surgery. After the second surgery, removed ovarian samples were evaluated for follicle counts, damage scores and other parameters. Primordial, preantral, small antral and large antral follicle counts were significantly higher in the detorsion + Allium sativum group. Degeneration, congestion, hemorrhage ,inflammation and total damage scores were significantly elevated in the detorsion only group compared to those for the detorsion + Allium sativum group. Finally, there was a significant correlation between AMH alterations and postoperative, preantral follicle count (p<0.05). As a conclusion detorsion + Allium sativum treatment may be effective in protecting the ovarian reserve after torsion. |
| author |
Güney,Gürhan Kaya,Cihan Yildirim,Serkan Oto,Gökhan Ekin,Suat Özdemir,Hülya |
| author_facet |
Güney,Gürhan Kaya,Cihan Yildirim,Serkan Oto,Gökhan Ekin,Suat Özdemir,Hülya |
| author_sort |
Güney,Gürhan |
| title |
Investigation of Allium sativum’s Protective Effect on Ovarian Reserve in an Experimental Ovarian Injury Model |
| title_short |
Investigation of Allium sativum’s Protective Effect on Ovarian Reserve in an Experimental Ovarian Injury Model |
| title_full |
Investigation of Allium sativum’s Protective Effect on Ovarian Reserve in an Experimental Ovarian Injury Model |
| title_fullStr |
Investigation of Allium sativum’s Protective Effect on Ovarian Reserve in an Experimental Ovarian Injury Model |
| title_full_unstemmed |
Investigation of Allium sativum’s Protective Effect on Ovarian Reserve in an Experimental Ovarian Injury Model |
| title_sort |
investigation of allium sativum’s protective effect on ovarian reserve in an experimental ovarian injury model |
| publisher |
Sociedad Chilena de Anatomía |
| publishDate |
2018 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022018000200395 |
| work_keys_str_mv |
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| _version_ |
1718445042410979328 |