Histomorphological Study of Placenta in Gestational Diabetes Mellitus

SUMMARY: Evidence from the literature shows that well-controlled glucose levels during pregnancy are usually associated with normal placental morphology. The aim of this study was to identify the lacental changes attributed to maternal hyperglycemia. A total of 20 placentae were selected for study f...

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Autores principales:	El-Sawy,Naser A., Iqbal,Mohammad Shahid, Alkushi,Abdullah G.
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2018
Materias:	Placenta Chorangiosis Trophoblast Villi
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022018000200687
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spelling	oai:scielo:S0717-950220180002006872019-09-16Histomorphological Study of Placenta in Gestational Diabetes MellitusEl-Sawy,Naser A.Iqbal,Mohammad ShahidAlkushi,Abdullah G. Placenta Chorangiosis Trophoblast Villi SUMMARY: Evidence from the literature shows that well-controlled glucose levels during pregnancy are usually associated with normal placental morphology. The aim of this study was to identify the lacental changes attributed to maternal hyperglycemia. A total of 20 placentae were selected for study from a tertiary care medical center in Makkah city, Saudi Arabia. Out of 20, 10 placentae were from patients diagnosed with GDM based on IADSPG criteria, and 10 placentae were from patients with normal pregnancies without GDM. The morphometric measurements were recorded. The mean weight of GDM placentae were more than the normal placentae. Upon histopathology, significant changes such as syncytial knots, cytotrophoblastic cell proliferation, fibrinoid necrosis, stromal fibrosis, and hyalinized villi were observed in GDM placentae. GDM produces significant morphological alterations in the placentae, which might affect the developing fetus.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.36 n.2 20182018-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022018000200687en10.4067/S0717-95022018000200687
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Placenta Chorangiosis Trophoblast Villi
spellingShingle	Placenta Chorangiosis Trophoblast Villi El-Sawy,Naser A. Iqbal,Mohammad Shahid Alkushi,Abdullah G. Histomorphological Study of Placenta in Gestational Diabetes Mellitus
description	SUMMARY: Evidence from the literature shows that well-controlled glucose levels during pregnancy are usually associated with normal placental morphology. The aim of this study was to identify the lacental changes attributed to maternal hyperglycemia. A total of 20 placentae were selected for study from a tertiary care medical center in Makkah city, Saudi Arabia. Out of 20, 10 placentae were from patients diagnosed with GDM based on IADSPG criteria, and 10 placentae were from patients with normal pregnancies without GDM. The morphometric measurements were recorded. The mean weight of GDM placentae were more than the normal placentae. Upon histopathology, significant changes such as syncytial knots, cytotrophoblastic cell proliferation, fibrinoid necrosis, stromal fibrosis, and hyalinized villi were observed in GDM placentae. GDM produces significant morphological alterations in the placentae, which might affect the developing fetus.
author	El-Sawy,Naser A. Iqbal,Mohammad Shahid Alkushi,Abdullah G.
author_facet	El-Sawy,Naser A. Iqbal,Mohammad Shahid Alkushi,Abdullah G.
author_sort	El-Sawy,Naser A.
title	Histomorphological Study of Placenta in Gestational Diabetes Mellitus
title_short	Histomorphological Study of Placenta in Gestational Diabetes Mellitus
title_full	Histomorphological Study of Placenta in Gestational Diabetes Mellitus
title_fullStr	Histomorphological Study of Placenta in Gestational Diabetes Mellitus
title_full_unstemmed	Histomorphological Study of Placenta in Gestational Diabetes Mellitus
title_sort	histomorphological study of placenta in gestational diabetes mellitus
publisher	Sociedad Chilena de Anatomía
publishDate	2018
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022018000200687
work_keys_str_mv	AT elsawynasera histomorphologicalstudyofplacentaingestationaldiabetesmellitus AT iqbalmohammadshahid histomorphologicalstudyofplacentaingestationaldiabetesmellitus AT alkushiabdullahg histomorphologicalstudyofplacentaingestationaldiabetesmellitus
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Histomorphological Study of Placenta in Gestational Diabetes Mellitus

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