Dayak Onions ( Eleutherine bulbosa (Mill.) Urb.) Bulbs Extracts Reduces Blood Pressure of Hypoestrogen Model Rats by Controlling Lipids Profile
SUMMARY: To determine the effects of 70 % ethanolic extract of Eleutherine bulbosa (Mill.) L. bulbs contained naphtoquinone in blood pressure and lipids profile level of ovariectomized rats. Thin layer chromatography was performed to analyze the content of the Eleutherine bulbosa (Mill.) bulbs extra...
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Sociedad Chilena de Anatomía
2018
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oai:scielo:S0717-950220180003010162019-09-16Dayak Onions ( Eleutherine bulbosa (Mill.) Urb.) Bulbs Extracts Reduces Blood Pressure of Hypoestrogen Model Rats by Controlling Lipids ProfileBahtiar,AntonChumala,Delvika Yessi Hypoestrogen Blood pressure Dayak Onions Eleutherinol Naphtoquinone SUMMARY: To determine the effects of 70 % ethanolic extract of Eleutherine bulbosa (Mill.) L. bulbs contained naphtoquinone in blood pressure and lipids profile level of ovariectomized rats. Thin layer chromatography was performed to analyze the content of the Eleutherine bulbosa (Mill.) bulbs extracts using Chloroform : Methanol (7:1) as eluent. This study used white female Sprague-Dawley rats which were divided into 6 groups: SHAM and OVX, both given 0.5 % carboxymethyl cellulose; the positive control group that was given tamoxifen (0.36 mg/200 g B.W.); the three various of doses of extract namely dose 1, 2, and 3 that were given 8, 12, and 18 mg/200 g BW respectively on day 29 until 50. All groups were ovariectomized on day 1, except sham group. Measurement of blood pressure were performed on the day before ovariectomy using non-invasive tool CODA®; and on the second, third, and fourth weeks post-ovariectomy. Three weeks after treatment of hypoestrogen rats by the dose 18 mg/200 g B.W, Eleutherine bulbosa extracts could decrease the systolic blood pressure level to 28.06 %, the diastolic to 30.47 %. Lipid profile of Dose 3 also showed recovery of Triglyceride, LDL and also Total Cholesterol. Eleutherine bulbosa extracts could improve blood pressure of ovariectomized rats by controlling lipids profile level.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.36 n.3 20182018-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022018000301016en10.4067/S0717-95022018000301016 |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
English |
| topic |
Hypoestrogen Blood pressure Dayak Onions Eleutherinol Naphtoquinone |
| spellingShingle |
Hypoestrogen Blood pressure Dayak Onions Eleutherinol Naphtoquinone Bahtiar,Anton Chumala,Delvika Yessi Dayak Onions ( Eleutherine bulbosa (Mill.) Urb.) Bulbs Extracts Reduces Blood Pressure of Hypoestrogen Model Rats by Controlling Lipids Profile |
| description |
SUMMARY: To determine the effects of 70 % ethanolic extract of Eleutherine bulbosa (Mill.) L. bulbs contained naphtoquinone in blood pressure and lipids profile level of ovariectomized rats. Thin layer chromatography was performed to analyze the content of the Eleutherine bulbosa (Mill.) bulbs extracts using Chloroform : Methanol (7:1) as eluent. This study used white female Sprague-Dawley rats which were divided into 6 groups: SHAM and OVX, both given 0.5 % carboxymethyl cellulose; the positive control group that was given tamoxifen (0.36 mg/200 g B.W.); the three various of doses of extract namely dose 1, 2, and 3 that were given 8, 12, and 18 mg/200 g BW respectively on day 29 until 50. All groups were ovariectomized on day 1, except sham group. Measurement of blood pressure were performed on the day before ovariectomy using non-invasive tool CODA®; and on the second, third, and fourth weeks post-ovariectomy. Three weeks after treatment of hypoestrogen rats by the dose 18 mg/200 g B.W, Eleutherine bulbosa extracts could decrease the systolic blood pressure level to 28.06 %, the diastolic to 30.47 %. Lipid profile of Dose 3 also showed recovery of Triglyceride, LDL and also Total Cholesterol. Eleutherine bulbosa extracts could improve blood pressure of ovariectomized rats by controlling lipids profile level. |
| author |
Bahtiar,Anton Chumala,Delvika Yessi |
| author_facet |
Bahtiar,Anton Chumala,Delvika Yessi |
| author_sort |
Bahtiar,Anton |
| title |
Dayak Onions ( Eleutherine bulbosa (Mill.) Urb.) Bulbs Extracts Reduces Blood Pressure of Hypoestrogen Model Rats by Controlling Lipids Profile |
| title_short |
Dayak Onions ( Eleutherine bulbosa (Mill.) Urb.) Bulbs Extracts Reduces Blood Pressure of Hypoestrogen Model Rats by Controlling Lipids Profile |
| title_full |
Dayak Onions ( Eleutherine bulbosa (Mill.) Urb.) Bulbs Extracts Reduces Blood Pressure of Hypoestrogen Model Rats by Controlling Lipids Profile |
| title_fullStr |
Dayak Onions ( Eleutherine bulbosa (Mill.) Urb.) Bulbs Extracts Reduces Blood Pressure of Hypoestrogen Model Rats by Controlling Lipids Profile |
| title_full_unstemmed |
Dayak Onions ( Eleutherine bulbosa (Mill.) Urb.) Bulbs Extracts Reduces Blood Pressure of Hypoestrogen Model Rats by Controlling Lipids Profile |
| title_sort |
dayak onions ( eleutherine bulbosa (mill.) urb.) bulbs extracts reduces blood pressure of hypoestrogen model rats by controlling lipids profile |
| publisher |
Sociedad Chilena de Anatomía |
| publishDate |
2018 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022018000301016 |
| work_keys_str_mv |
AT bahtiaranton dayakonionseleutherinebulbosamillurbbulbsextractsreducesbloodpressureofhypoestrogenmodelratsbycontrollinglipidsprofile AT chumaladelvikayessi dayakonionseleutherinebulbosamillurbbulbsextractsreducesbloodpressureofhypoestrogenmodelratsbycontrollinglipidsprofile |
| _version_ |
1718445059985113088 |