The Cortical Matrix of Femur in Adult-Aged Wistar Rats is Critically Affected by Maternal Malnutrition During Lactation Period

SUMMARY: Osteoporosis is associated with poor dietary habits. Malnutrition is characterized as a deficit on the intake of necessary nutrients that are essential for optimal health maintenance. It is known that malnutrition during the lactation period can affect the offspring. The present study aims...

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Autores principales:	Babinski,Marcio Antonio, Andrade,Marcio Vinicius Viana, Fernandes,Mario Augusto Sereno, Mendes,Jorge Gilberto Cipriano, Babinski,Monique da Silva Dias, Pires,Lucas Alves Sarmento, Gameiro,Vinicius Schott
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2018
Materias:	Bone remodeling Bone matrix Undernutrition Osteoporosis Wistar rats
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022018000401285
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spelling	oai:scielo:S0717-950220180004012852019-09-16The Cortical Matrix of Femur in Adult-Aged Wistar Rats is Critically Affected by Maternal Malnutrition During Lactation PeriodBabinski,Marcio AntonioAndrade,Marcio Vinicius VianaFernandes,Mario Augusto SerenoMendes,Jorge Gilberto CiprianoBabinski,Monique da Silva DiasPires,Lucas Alves SarmentoGameiro,Vinicius Schott Bone remodeling Bone matrix Undernutrition Osteoporosis Wistar rats SUMMARY: Osteoporosis is associated with poor dietary habits. Malnutrition is characterized as a deficit on the intake of necessary nutrients that are essential for optimal health maintenance. It is known that malnutrition during the lactation period can affect the offspring. The present study aims to evaluate the chronic effects caused by maternal energy-protein restriction during lactation period in the offspring. At parturition, Wistar rat dams were divided in three groups: (1) Control group (C) - which received a 23 % protein diet without restrictions; (2) Protein-Energy restriction group (PER)- which received a 8 % protein diet; (3) Energy restriction group (ER) which received a 23 % protein diet in limited amounts, according to the ingestion of the second group. Each group had 12 pups. After weaning, all pups received free access to a 23 % protein diet until 180 days and then were euthanized. Their femur was excised, decalcified, histologically processed and analyzed under a microscope. The measurements of the osteon lacunae on the C, ER and PER groups were, respectively: 2.1 µm, 10.9 µm and 14.7 µm (p<0.05). A poor ingestion of proteins and calories during lactation period provoked critical and permanent changes on the bone matrix of the femur, which simulated osteoporosis.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.36 n.4 20182018-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022018000401285en10.4067/S0717-95022018000401285
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Bone remodeling Bone matrix Undernutrition Osteoporosis Wistar rats
spellingShingle	Bone remodeling Bone matrix Undernutrition Osteoporosis Wistar rats Babinski,Marcio Antonio Andrade,Marcio Vinicius Viana Fernandes,Mario Augusto Sereno Mendes,Jorge Gilberto Cipriano Babinski,Monique da Silva Dias Pires,Lucas Alves Sarmento Gameiro,Vinicius Schott The Cortical Matrix of Femur in Adult-Aged Wistar Rats is Critically Affected by Maternal Malnutrition During Lactation Period
description	SUMMARY: Osteoporosis is associated with poor dietary habits. Malnutrition is characterized as a deficit on the intake of necessary nutrients that are essential for optimal health maintenance. It is known that malnutrition during the lactation period can affect the offspring. The present study aims to evaluate the chronic effects caused by maternal energy-protein restriction during lactation period in the offspring. At parturition, Wistar rat dams were divided in three groups: (1) Control group (C) - which received a 23 % protein diet without restrictions; (2) Protein-Energy restriction group (PER)- which received a 8 % protein diet; (3) Energy restriction group (ER) which received a 23 % protein diet in limited amounts, according to the ingestion of the second group. Each group had 12 pups. After weaning, all pups received free access to a 23 % protein diet until 180 days and then were euthanized. Their femur was excised, decalcified, histologically processed and analyzed under a microscope. The measurements of the osteon lacunae on the C, ER and PER groups were, respectively: 2.1 µm, 10.9 µm and 14.7 µm (p<0.05). A poor ingestion of proteins and calories during lactation period provoked critical and permanent changes on the bone matrix of the femur, which simulated osteoporosis.
author	Babinski,Marcio Antonio Andrade,Marcio Vinicius Viana Fernandes,Mario Augusto Sereno Mendes,Jorge Gilberto Cipriano Babinski,Monique da Silva Dias Pires,Lucas Alves Sarmento Gameiro,Vinicius Schott
author_facet	Babinski,Marcio Antonio Andrade,Marcio Vinicius Viana Fernandes,Mario Augusto Sereno Mendes,Jorge Gilberto Cipriano Babinski,Monique da Silva Dias Pires,Lucas Alves Sarmento Gameiro,Vinicius Schott
author_sort	Babinski,Marcio Antonio
title	The Cortical Matrix of Femur in Adult-Aged Wistar Rats is Critically Affected by Maternal Malnutrition During Lactation Period
title_short	The Cortical Matrix of Femur in Adult-Aged Wistar Rats is Critically Affected by Maternal Malnutrition During Lactation Period
title_full	The Cortical Matrix of Femur in Adult-Aged Wistar Rats is Critically Affected by Maternal Malnutrition During Lactation Period
title_fullStr	The Cortical Matrix of Femur in Adult-Aged Wistar Rats is Critically Affected by Maternal Malnutrition During Lactation Period
title_full_unstemmed	The Cortical Matrix of Femur in Adult-Aged Wistar Rats is Critically Affected by Maternal Malnutrition During Lactation Period
title_sort	cortical matrix of femur in adult-aged wistar rats is critically affected by maternal malnutrition during lactation period
publisher	Sociedad Chilena de Anatomía
publishDate	2018
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022018000401285
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The Cortical Matrix of Femur in Adult-Aged Wistar Rats is Critically Affected by Maternal Malnutrition During Lactation Period

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