Immunoglobulin G4-Related Disease of the Maxillofacial Region. A Rare Case

SUMMARY: IgG4-related disease is a systemic, multifocal, immune-mediated disorder that can affect multiple organs and may present as a tumor, with rare cases described in the maxillofacial region. A female patient, 53 years old, presenting tumor-like mass in the right mandibular region. Magnetic res...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Fonseca,Vitor José, Manzano-de-Moraes,Afonso Celso, Olate,Sergio, Asprino,Luciana, de-Moraes,Márcio
Lenguaje:English
Publicado: Sociedad Chilena de Anatomía 2018
Materias:
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022018000401509
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:scielo:S0717-95022018000401509
record_format dspace
spelling oai:scielo:S0717-950220180004015092019-09-16Immunoglobulin G4-Related Disease of the Maxillofacial Region. A Rare CaseFonseca,Vitor JoséManzano-de-Moraes,Afonso CelsoOlate,SergioAsprino,Lucianade-Moraes,Márcio IgG4 IgG4-related disease Tumor SUMMARY: IgG4-related disease is a systemic, multifocal, immune-mediated disorder that can affect multiple organs and may present as a tumor, with rare cases described in the maxillofacial region. A female patient, 53 years old, presenting tumor-like mass in the right mandibular region. Magnetic resonance imaging suggested well circumscribed nodular lesion adjacent to the branch / body of the mandible, extending posteriorly to the masseter muscle. During the surgical procedure of excision, a lesion was observed adhering to the right masseter muscle, but it was possible to remove it completely. Histopathological and immunehistochemical analysis suggested diagnosis of IgG4-related disease, furthermore, IgG4 serum count was increased. Actually, the patient continues on periodical followups in our service and by other specialties. Can be concluded that precise diagnosis of this pathology depends on many factors, being challenging and the treatment involves multidisciplinary evaluation due to the possibility of involvement of several other organs.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.36 n.4 20182018-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022018000401509en10.4067/S0717-95022018000401509
institution Scielo Chile
collection Scielo Chile
language English
topic IgG4
IgG4-related disease
Tumor
spellingShingle IgG4
IgG4-related disease
Tumor
Fonseca,Vitor José
Manzano-de-Moraes,Afonso Celso
Olate,Sergio
Asprino,Luciana
de-Moraes,Márcio
Immunoglobulin G4-Related Disease of the Maxillofacial Region. A Rare Case
description SUMMARY: IgG4-related disease is a systemic, multifocal, immune-mediated disorder that can affect multiple organs and may present as a tumor, with rare cases described in the maxillofacial region. A female patient, 53 years old, presenting tumor-like mass in the right mandibular region. Magnetic resonance imaging suggested well circumscribed nodular lesion adjacent to the branch / body of the mandible, extending posteriorly to the masseter muscle. During the surgical procedure of excision, a lesion was observed adhering to the right masseter muscle, but it was possible to remove it completely. Histopathological and immunehistochemical analysis suggested diagnosis of IgG4-related disease, furthermore, IgG4 serum count was increased. Actually, the patient continues on periodical followups in our service and by other specialties. Can be concluded that precise diagnosis of this pathology depends on many factors, being challenging and the treatment involves multidisciplinary evaluation due to the possibility of involvement of several other organs.
author Fonseca,Vitor José
Manzano-de-Moraes,Afonso Celso
Olate,Sergio
Asprino,Luciana
de-Moraes,Márcio
author_facet Fonseca,Vitor José
Manzano-de-Moraes,Afonso Celso
Olate,Sergio
Asprino,Luciana
de-Moraes,Márcio
author_sort Fonseca,Vitor José
title Immunoglobulin G4-Related Disease of the Maxillofacial Region. A Rare Case
title_short Immunoglobulin G4-Related Disease of the Maxillofacial Region. A Rare Case
title_full Immunoglobulin G4-Related Disease of the Maxillofacial Region. A Rare Case
title_fullStr Immunoglobulin G4-Related Disease of the Maxillofacial Region. A Rare Case
title_full_unstemmed Immunoglobulin G4-Related Disease of the Maxillofacial Region. A Rare Case
title_sort immunoglobulin g4-related disease of the maxillofacial region. a rare case
publisher Sociedad Chilena de Anatomía
publishDate 2018
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022018000401509
work_keys_str_mv AT fonsecavitorjose immunoglobuling4relateddiseaseofthemaxillofacialregionararecase
AT manzanodemoraesafonsocelso immunoglobuling4relateddiseaseofthemaxillofacialregionararecase
AT olatesergio immunoglobuling4relateddiseaseofthemaxillofacialregionararecase
AT asprinoluciana immunoglobuling4relateddiseaseofthemaxillofacialregionararecase
AT demoraesmarcio immunoglobuling4relateddiseaseofthemaxillofacialregionararecase
_version_ 1718445079156228096