Sugarcane Biopolymer as a Guide Tube in the Regeneration of Peripheral Nerves in Rats

SUMMARY: Peripheral nerve regeneration is a serious clinical problem. The goal of this work was to evaluate comparatively a biopolymer tube of sugarcane with an expanded polyethylene tube as a tube guide in peripheral nerve regeneration. Fourteen male albino Wistar rats were used, separated into thr...

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Autores principales:	da-Silva,Ivson Bezerra, Lós,Deniele Bezerra, de-Andrade,Rodrigo Fragoso, Maciel,Carla do Couto Soares, de-Castro,Célia Maria Machado Barbosa, Aguiar,José Lamartine de Andrade, de-Moraes,Silvia Regina Arruda
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2019
Materias:	Nerve regeneration Biomaterials Biopolymer Sugarcane Sciatic nerve
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022019000100289
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spelling	oai:scielo:S0717-950220190001002892019-09-11Sugarcane Biopolymer as a Guide Tube in the Regeneration of Peripheral Nerves in Ratsda-Silva,Ivson BezerraLós,Deniele Bezerrade-Andrade,Rodrigo FragosoMaciel,Carla do Couto Soaresde-Castro,Célia Maria Machado BarbosaAguiar,José Lamartine de Andradede-Moraes,Silvia Regina Arruda Nerve regeneration Biomaterials Biopolymer Sugarcane Sciatic nerve SUMMARY: Peripheral nerve regeneration is a serious clinical problem. The goal of this work was to evaluate comparatively a biopolymer tube of sugarcane with an expanded polyethylene tube as a tube guide in peripheral nerve regeneration. Fourteen male albino Wistar rats were used, separated into three different groups: control (CG), lesion + polyethylene tube (PG) and lesion + sugarcane biopolymer (SBG). At 60 days old, animals from the PG and SBG underwent surgery for tubulization of the sciatic nerve, and 60 days after the injury they were sacrificed for collection of the nerve. In the analysis of the number of nerve fibers, a smaller number was seen in the PG and SBG groups compared to the CG, no difference was seen between the PG and SBG groups (p<0.05). With regard to the number of blood vessels, the SBG group had a larger number than the CG and PG groups (p<0.05). The SBG also presented increase on axonal diameter and G -ratio compared to PG (p<0.05). Taken together these data revealed that biopolymer tube favors a suitable environment for peripheral nerve regeneration.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.37 n.1 20192019-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022019000100289en10.4067/S0717-95022019000100289
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Nerve regeneration Biomaterials Biopolymer Sugarcane Sciatic nerve
spellingShingle	Nerve regeneration Biomaterials Biopolymer Sugarcane Sciatic nerve da-Silva,Ivson Bezerra Lós,Deniele Bezerra de-Andrade,Rodrigo Fragoso Maciel,Carla do Couto Soares de-Castro,Célia Maria Machado Barbosa Aguiar,José Lamartine de Andrade de-Moraes,Silvia Regina Arruda Sugarcane Biopolymer as a Guide Tube in the Regeneration of Peripheral Nerves in Rats
description	SUMMARY: Peripheral nerve regeneration is a serious clinical problem. The goal of this work was to evaluate comparatively a biopolymer tube of sugarcane with an expanded polyethylene tube as a tube guide in peripheral nerve regeneration. Fourteen male albino Wistar rats were used, separated into three different groups: control (CG), lesion + polyethylene tube (PG) and lesion + sugarcane biopolymer (SBG). At 60 days old, animals from the PG and SBG underwent surgery for tubulization of the sciatic nerve, and 60 days after the injury they were sacrificed for collection of the nerve. In the analysis of the number of nerve fibers, a smaller number was seen in the PG and SBG groups compared to the CG, no difference was seen between the PG and SBG groups (p<0.05). With regard to the number of blood vessels, the SBG group had a larger number than the CG and PG groups (p<0.05). The SBG also presented increase on axonal diameter and G -ratio compared to PG (p<0.05). Taken together these data revealed that biopolymer tube favors a suitable environment for peripheral nerve regeneration.
author	da-Silva,Ivson Bezerra Lós,Deniele Bezerra de-Andrade,Rodrigo Fragoso Maciel,Carla do Couto Soares de-Castro,Célia Maria Machado Barbosa Aguiar,José Lamartine de Andrade de-Moraes,Silvia Regina Arruda
author_facet	da-Silva,Ivson Bezerra Lós,Deniele Bezerra de-Andrade,Rodrigo Fragoso Maciel,Carla do Couto Soares de-Castro,Célia Maria Machado Barbosa Aguiar,José Lamartine de Andrade de-Moraes,Silvia Regina Arruda
author_sort	da-Silva,Ivson Bezerra
title	Sugarcane Biopolymer as a Guide Tube in the Regeneration of Peripheral Nerves in Rats
title_short	Sugarcane Biopolymer as a Guide Tube in the Regeneration of Peripheral Nerves in Rats
title_full	Sugarcane Biopolymer as a Guide Tube in the Regeneration of Peripheral Nerves in Rats
title_fullStr	Sugarcane Biopolymer as a Guide Tube in the Regeneration of Peripheral Nerves in Rats
title_full_unstemmed	Sugarcane Biopolymer as a Guide Tube in the Regeneration of Peripheral Nerves in Rats
title_sort	sugarcane biopolymer as a guide tube in the regeneration of peripheral nerves in rats
publisher	Sociedad Chilena de Anatomía
publishDate	2019
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022019000100289
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Sugarcane Biopolymer as a Guide Tube in the Regeneration of Peripheral Nerves in Rats

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