Investigation of the Effect of GnRH (Deslorelin) on the Histochemical Structure of Salivary Glands in Rats

SUMMARY: This study was planned to determine the histochemical alterations of the submandibular gland by implantation of long-term GnRH (deslorelin 4.7 mg). Eighteen Wistar albino rats were used in the study. Alcian blue (AB; pH: 2.5), periodic acid-Schiff (PAS) staining was performed to determine t...

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Autores principales:	Uslu,Sema, Çakmak,Gamze, Yörük,Mecit
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2019
Materias:	Submandibular gland GnRH Histochemistry Lectin Rat
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022019000301008
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spelling	oai:scielo:S0717-950220190003010082019-09-11Investigation of the Effect of GnRH (Deslorelin) on the Histochemical Structure of Salivary Glands in RatsUslu,SemaÇakmak,GamzeYörük,Mecit Submandibular gland GnRH Histochemistry Lectin Rat SUMMARY: This study was planned to determine the histochemical alterations of the submandibular gland by implantation of long-term GnRH (deslorelin 4.7 mg). Eighteen Wistar albino rats were used in the study. Alcian blue (AB; pH: 2.5), periodic acid-Schiff (PAS) staining was performed to determine the microscopic structure and histochemical structure of the GI submandibular gland. The Avidin-Biotin Complex (ABC) method was used to determine the immunohistochemical reactivity of lectin. After GnRH implantation, the organs were examined and atrophies were observed in organs. In the group in which the implants were removed, it was determined that there was no atrophy; organ structures and microscopic examination were similar to the control group. At the end of the study, submandibular gland was fixed in 10 % buffered formaldehyde. In three groups, PAS and AB histochemical staining revealed similar reactions. Immunohistochemically, lectin activity was found to react positively.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.37 n.3 20192019-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022019000301008en10.4067/S0717-95022019000301008
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Submandibular gland GnRH Histochemistry Lectin Rat
spellingShingle	Submandibular gland GnRH Histochemistry Lectin Rat Uslu,Sema Çakmak,Gamze Yörük,Mecit Investigation of the Effect of GnRH (Deslorelin) on the Histochemical Structure of Salivary Glands in Rats
description	SUMMARY: This study was planned to determine the histochemical alterations of the submandibular gland by implantation of long-term GnRH (deslorelin 4.7 mg). Eighteen Wistar albino rats were used in the study. Alcian blue (AB; pH: 2.5), periodic acid-Schiff (PAS) staining was performed to determine the microscopic structure and histochemical structure of the GI submandibular gland. The Avidin-Biotin Complex (ABC) method was used to determine the immunohistochemical reactivity of lectin. After GnRH implantation, the organs were examined and atrophies were observed in organs. In the group in which the implants were removed, it was determined that there was no atrophy; organ structures and microscopic examination were similar to the control group. At the end of the study, submandibular gland was fixed in 10 % buffered formaldehyde. In three groups, PAS and AB histochemical staining revealed similar reactions. Immunohistochemically, lectin activity was found to react positively.
author	Uslu,Sema Çakmak,Gamze Yörük,Mecit
author_facet	Uslu,Sema Çakmak,Gamze Yörük,Mecit
author_sort	Uslu,Sema
title	Investigation of the Effect of GnRH (Deslorelin) on the Histochemical Structure of Salivary Glands in Rats
title_short	Investigation of the Effect of GnRH (Deslorelin) on the Histochemical Structure of Salivary Glands in Rats
title_full	Investigation of the Effect of GnRH (Deslorelin) on the Histochemical Structure of Salivary Glands in Rats
title_fullStr	Investigation of the Effect of GnRH (Deslorelin) on the Histochemical Structure of Salivary Glands in Rats
title_full_unstemmed	Investigation of the Effect of GnRH (Deslorelin) on the Histochemical Structure of Salivary Glands in Rats
title_sort	investigation of the effect of gnrh (deslorelin) on the histochemical structure of salivary glands in rats
publisher	Sociedad Chilena de Anatomía
publishDate	2019
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022019000301008
work_keys_str_mv	AT uslusema investigationoftheeffectofgnrhdeslorelinonthehistochemicalstructureofsalivaryglandsinrats AT cakmakgamze investigationoftheeffectofgnrhdeslorelinonthehistochemicalstructureofsalivaryglandsinrats AT yorukmecit investigationoftheeffectofgnrhdeslorelinonthehistochemicalstructureofsalivaryglandsinrats
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Investigation of the Effect of GnRH (Deslorelin) on the Histochemical Structure of Salivary Glands in Rats

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