Pancreatic Islet Stereology: Estimation of Beta Cells Mass

SUMMARY: Obesity and its comorbidities are becoming epidemic in the Western world. Beta cell mass estimation is an important indicator to track the progression of insulin resistance/type 2 diabetes, particularly in experimental studies, where it can be performed with stereological tools in an unbias...

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Autores principales:	Marinho,Thatiany de Souza, Aguila,Marcia Barbosa, Mandarim-de-Lacerda,Carlos Alberto
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2019
Materias:	Pancreatic islet Beta cell Stereology Obesity Cell biology
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022019000401331
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spelling	oai:scielo:S0717-950220190004013312019-09-11Pancreatic Islet Stereology: Estimation of Beta Cells MassMarinho,Thatiany de SouzaAguila,Marcia BarbosaMandarim-de-Lacerda,Carlos Alberto Pancreatic islet Beta cell Stereology Obesity Cell biology SUMMARY: Obesity and its comorbidities are becoming epidemic in the Western world. Beta cell mass estimation is an important indicator to track the progression of insulin resistance/type 2 diabetes, particularly in experimental studies, where it can be performed with stereological tools in an unbiased way. In this work, we present a simple protocol that can contribute to doing the practice of estimating the mass of beta cells more frequent and reproducible. As with any quantitative study, the necessary precautions regarding sampling and randomness must be respected.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.37 n.4 20192019-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022019000401331en10.4067/S0717-95022019000401331
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Pancreatic islet Beta cell Stereology Obesity Cell biology
spellingShingle	Pancreatic islet Beta cell Stereology Obesity Cell biology Marinho,Thatiany de Souza Aguila,Marcia Barbosa Mandarim-de-Lacerda,Carlos Alberto Pancreatic Islet Stereology: Estimation of Beta Cells Mass
description	SUMMARY: Obesity and its comorbidities are becoming epidemic in the Western world. Beta cell mass estimation is an important indicator to track the progression of insulin resistance/type 2 diabetes, particularly in experimental studies, where it can be performed with stereological tools in an unbiased way. In this work, we present a simple protocol that can contribute to doing the practice of estimating the mass of beta cells more frequent and reproducible. As with any quantitative study, the necessary precautions regarding sampling and randomness must be respected.
author	Marinho,Thatiany de Souza Aguila,Marcia Barbosa Mandarim-de-Lacerda,Carlos Alberto
author_facet	Marinho,Thatiany de Souza Aguila,Marcia Barbosa Mandarim-de-Lacerda,Carlos Alberto
author_sort	Marinho,Thatiany de Souza
title	Pancreatic Islet Stereology: Estimation of Beta Cells Mass
title_short	Pancreatic Islet Stereology: Estimation of Beta Cells Mass
title_full	Pancreatic Islet Stereology: Estimation of Beta Cells Mass
title_fullStr	Pancreatic Islet Stereology: Estimation of Beta Cells Mass
title_full_unstemmed	Pancreatic Islet Stereology: Estimation of Beta Cells Mass
title_sort	pancreatic islet stereology: estimation of beta cells mass
publisher	Sociedad Chilena de Anatomía
publishDate	2019
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022019000401331
work_keys_str_mv	AT marinhothatianydesouza pancreaticisletstereologyestimationofbetacellsmass AT aguilamarciabarbosa pancreaticisletstereologyestimationofbetacellsmass AT mandarimdelacerdacarlosalberto pancreaticisletstereologyestimationofbetacellsmass
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Pancreatic Islet Stereology: Estimation of Beta Cells Mass

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