Autophagy Inhibitor 3-Methyladenine could not Modulate Rotenone Neurotoxicity in Primary Mesencephalic Cell Culture

Autophagy Inhibitor 3-Methyladenine could not Modulate Rotenone Neurotoxicity in Primary Mesencephalic Cell Culture

SUMMARY: Dysregulated autophagy, whether excessive or downregulated, has been thought to be associated with neurodegenerative disorders including Parkinson’s disease. Accordingly, the present study was carried out to investigate whether 3-methyladenine, an autophagy inhibitor, can modulate...

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Autores principales: Radad,Khaled, Al-Shraim,Mubarak, Al-Emam,Ahmed, Rausch,Wolf-Dieter, Moldzio,Rudolf
Lenguaje:English
Publicado: Sociedad Chilena de Anatomía 2020
Materias:
Autophagy
Dopaminergic neurons
Parkinson’s disease
Rotenone
3-methyladenine
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022020000300530
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