Effects of Dexamethasone on the Morphometry and Biometry of Immune Organs of Broiler Chicken

SUMMARY: The study was conducted to examine the histological changes i.e. morphology and biometry of immune organs (thymus, spleen and bursa cloacalis or «Fabricius») of broilers in response to dietary dexamethasone (DEX). The day old chicks were obtained from the commercial hatchery and randomly di...

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Autores principales:	Sultana,Nasrin, Amin,Tanjina, Afrose,Marzia, Aqter-Rony,Sharmin, Rafiq,Kazi
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2020
Materias:	Broiler Dexamethasone Immune organs
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022020000401032
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spelling	oai:scielo:S0717-950220200004010322020-09-08Effects of Dexamethasone on the Morphometry and Biometry of Immune Organs of Broiler ChickenSultana,NasrinAmin,TanjinaAfrose,MarziaAqter-Rony,SharminRafiq,Kazi Broiler Dexamethasone Immune organs SUMMARY: The study was conducted to examine the histological changes i.e. morphology and biometry of immune organs (thymus, spleen and bursa cloacalis or «Fabricius») of broilers in response to dietary dexamethasone (DEX). The day old chicks were obtained from the commercial hatchery and randomly divided into two groups i.e. control and experimental or treated group. The control group was reared on commercial broiler ration and the experimental group (n=25) was maintained on commercial broiler ration with corticosteroid (Dexamethasone-Decason, BP 0.5 mg, Opsonin @ 7 mg/kg feed). Samples (bursa cloacalis, spleen, and thymus) were collected from the ten control and ten experimental broilers at 14 and 28 days of experiment; then tissues were stained with Hematoxylin and Eosin. The biometric measurements of the samples were performed by the calibrated stage micrometer. Finally, the obtained data were analyzed using GraphPad Prism 8 software. In DEX treated group, the morphology of thymus, spleen and bursa cloacalis did not show any abnormal alterations. But their development rate was slower on visual inspection in DEX treated group. The length and width of bursal follicle of bursa cloacalis, thymic lobule of thymus and white pulp of spleen were statistically consisted but numerically decreased in DEX treated group than the control. The present findings suggested that DEX does not affect the histological architectures of immune organs except causing developmental arrest. Numerical decrease in the biometry of immune organs indicates that DEX causes apoptosis of immune cells in lymphoid organs of broiler.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.38 n.4 20202020-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022020000401032en10.4067/S0717-95022020000401032
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Broiler Dexamethasone Immune organs
spellingShingle	Broiler Dexamethasone Immune organs Sultana,Nasrin Amin,Tanjina Afrose,Marzia Aqter-Rony,Sharmin Rafiq,Kazi Effects of Dexamethasone on the Morphometry and Biometry of Immune Organs of Broiler Chicken
description	SUMMARY: The study was conducted to examine the histological changes i.e. morphology and biometry of immune organs (thymus, spleen and bursa cloacalis or «Fabricius») of broilers in response to dietary dexamethasone (DEX). The day old chicks were obtained from the commercial hatchery and randomly divided into two groups i.e. control and experimental or treated group. The control group was reared on commercial broiler ration and the experimental group (n=25) was maintained on commercial broiler ration with corticosteroid (Dexamethasone-Decason, BP 0.5 mg, Opsonin @ 7 mg/kg feed). Samples (bursa cloacalis, spleen, and thymus) were collected from the ten control and ten experimental broilers at 14 and 28 days of experiment; then tissues were stained with Hematoxylin and Eosin. The biometric measurements of the samples were performed by the calibrated stage micrometer. Finally, the obtained data were analyzed using GraphPad Prism 8 software. In DEX treated group, the morphology of thymus, spleen and bursa cloacalis did not show any abnormal alterations. But their development rate was slower on visual inspection in DEX treated group. The length and width of bursal follicle of bursa cloacalis, thymic lobule of thymus and white pulp of spleen were statistically consisted but numerically decreased in DEX treated group than the control. The present findings suggested that DEX does not affect the histological architectures of immune organs except causing developmental arrest. Numerical decrease in the biometry of immune organs indicates that DEX causes apoptosis of immune cells in lymphoid organs of broiler.
author	Sultana,Nasrin Amin,Tanjina Afrose,Marzia Aqter-Rony,Sharmin Rafiq,Kazi
author_facet	Sultana,Nasrin Amin,Tanjina Afrose,Marzia Aqter-Rony,Sharmin Rafiq,Kazi
author_sort	Sultana,Nasrin
title	Effects of Dexamethasone on the Morphometry and Biometry of Immune Organs of Broiler Chicken
title_short	Effects of Dexamethasone on the Morphometry and Biometry of Immune Organs of Broiler Chicken
title_full	Effects of Dexamethasone on the Morphometry and Biometry of Immune Organs of Broiler Chicken
title_fullStr	Effects of Dexamethasone on the Morphometry and Biometry of Immune Organs of Broiler Chicken
title_full_unstemmed	Effects of Dexamethasone on the Morphometry and Biometry of Immune Organs of Broiler Chicken
title_sort	effects of dexamethasone on the morphometry and biometry of immune organs of broiler chicken
publisher	Sociedad Chilena de Anatomía
publishDate	2020
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022020000401032
work_keys_str_mv	AT sultananasrin effectsofdexamethasoneonthemorphometryandbiometryofimmuneorgansofbroilerchicken AT amintanjina effectsofdexamethasoneonthemorphometryandbiometryofimmuneorgansofbroilerchicken AT afrosemarzia effectsofdexamethasoneonthemorphometryandbiometryofimmuneorgansofbroilerchicken AT aqterronysharmin effectsofdexamethasoneonthemorphometryandbiometryofimmuneorgansofbroilerchicken AT rafiqkazi effectsofdexamethasoneonthemorphometryandbiometryofimmuneorgansofbroilerchicken
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Effects of Dexamethasone on the Morphometry and Biometry of Immune Organs of Broiler Chicken

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