Results of Surgical Treatment of Advanced Gastric Cancer. Case Series with Follow-Up

SUMMARY: Gastric cancer (CG) is the second leading cause of cancer deaths. The best treatment option for patients with advanced GC (AGC) is still surgery, which involves performing a gastrectomy and D2 lymphadenectomy (D2L). The aim of this study was to determine postoperative morbidity (POM) and 5-...

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Autores principales:	Manterola,Carlos, Claros,Nataniel
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2020
Materias:	"Stomach Neoplasms"[Mesh]) AND "Stomach Neoplasms/surgery"[Mesh] “Lymph Node Excision"[Mesh] Gastric Cancers Surgery, Lymphadenectomy
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022020000501479
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spelling	oai:scielo:S0717-950220200005014792021-06-10Results of Surgical Treatment of Advanced Gastric Cancer. Case Series with Follow-UpManterola,CarlosClaros,Nataniel "Stomach Neoplasms"[Mesh]) AND "Stomach Neoplasms/surgery"[Mesh] “Lymph Node Excision"[Mesh] Gastric Cancers Surgery, Lymphadenectomy SUMMARY: Gastric cancer (CG) is the second leading cause of cancer deaths. The best treatment option for patients with advanced GC (AGC) is still surgery, which involves performing a gastrectomy and D2 lymphadenectomy (D2L). The aim of this study was to determine postoperative morbidity (POM) and 5-year OS in patients resected by AGC without neoadjuvant. Case series with follow-up of patients with AGC undergoing total or subtotal gastrectomies and D2L, consecutively at RedSalud Mayor Temuco Clinic, between 2008 and 2019. The outcome variables were POM and 5-year OS. Other variables of interest were surgical time, number of resected lymph nodes, hospital stay, and recurrence. Descriptive statistics was used, and Kaplan-Meier curves were calculated. In this analysis 38 patients (71.1 % men), with a median age of 65 years, were operated. The most frequent location was subcardial (50.0 %). The most frequent type of resection was total gastrectomy (60.5 %). The median of surgical time, number of resected lymph nodes and hospital stay; was 190 min, 32 and 6 days respectively. MPO was 18.4 %. With a median follow-up of 28 months, a recurrence of 44.7 % was verified; and 5-year OS for stages IIIA, IIIB and IV were 53.3 %, 46.1 % and 20.0 % respectively (p= 0,007). The results achieved, in terms of POM and OS series were similar to national and international series in which neoadjuvant therapies have not been applied.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.38 n.5 20202020-10-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022020000501479en10.4067/S0717-95022020000501479
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	"Stomach Neoplasms"[Mesh]) AND "Stomach Neoplasms/surgery"[Mesh] “Lymph Node Excision"[Mesh] Gastric Cancers Surgery, Lymphadenectomy
spellingShingle	"Stomach Neoplasms"[Mesh]) AND "Stomach Neoplasms/surgery"[Mesh] “Lymph Node Excision"[Mesh] Gastric Cancers Surgery, Lymphadenectomy Manterola,Carlos Claros,Nataniel Results of Surgical Treatment of Advanced Gastric Cancer. Case Series with Follow-Up
description	SUMMARY: Gastric cancer (CG) is the second leading cause of cancer deaths. The best treatment option for patients with advanced GC (AGC) is still surgery, which involves performing a gastrectomy and D2 lymphadenectomy (D2L). The aim of this study was to determine postoperative morbidity (POM) and 5-year OS in patients resected by AGC without neoadjuvant. Case series with follow-up of patients with AGC undergoing total or subtotal gastrectomies and D2L, consecutively at RedSalud Mayor Temuco Clinic, between 2008 and 2019. The outcome variables were POM and 5-year OS. Other variables of interest were surgical time, number of resected lymph nodes, hospital stay, and recurrence. Descriptive statistics was used, and Kaplan-Meier curves were calculated. In this analysis 38 patients (71.1 % men), with a median age of 65 years, were operated. The most frequent location was subcardial (50.0 %). The most frequent type of resection was total gastrectomy (60.5 %). The median of surgical time, number of resected lymph nodes and hospital stay; was 190 min, 32 and 6 days respectively. MPO was 18.4 %. With a median follow-up of 28 months, a recurrence of 44.7 % was verified; and 5-year OS for stages IIIA, IIIB and IV were 53.3 %, 46.1 % and 20.0 % respectively (p= 0,007). The results achieved, in terms of POM and OS series were similar to national and international series in which neoadjuvant therapies have not been applied.
author	Manterola,Carlos Claros,Nataniel
author_facet	Manterola,Carlos Claros,Nataniel
author_sort	Manterola,Carlos
title	Results of Surgical Treatment of Advanced Gastric Cancer. Case Series with Follow-Up
title_short	Results of Surgical Treatment of Advanced Gastric Cancer. Case Series with Follow-Up
title_full	Results of Surgical Treatment of Advanced Gastric Cancer. Case Series with Follow-Up
title_fullStr	Results of Surgical Treatment of Advanced Gastric Cancer. Case Series with Follow-Up
title_full_unstemmed	Results of Surgical Treatment of Advanced Gastric Cancer. Case Series with Follow-Up
title_sort	results of surgical treatment of advanced gastric cancer. case series with follow-up
publisher	Sociedad Chilena de Anatomía
publishDate	2020
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022020000501479
work_keys_str_mv	AT manterolacarlos resultsofsurgicaltreatmentofadvancedgastriccancercaseserieswithfollowup AT clarosnataniel resultsofsurgicaltreatmentofadvancedgastriccancercaseserieswithfollowup
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Results of Surgical Treatment of Advanced Gastric Cancer. Case Series with Follow-Up

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