The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor

SUMMARY: The study reported the influence of the high and acute dose of Letrozole on the testis morphology in paca (Cuniculus paca), an aromatase inhibitor that reduces the endogenous estrogen, the essential hormone for spermatogenesis. Morphological changes were observed in seminiferous epithelium...

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Autores principales: Simões,Luciana Senna, Sasahara,Taís Harumi de Castro, Favaron,Phelipe Oliveira, Leal,Leonardo Martins, Oliveira,Fabrício Singaretti de, Fratini,Paula, Berger,Trish, Machado,Marcia Rita Fernandes, Miglino,Maria Angélica
Lenguaje:English
Publicado: Sociedad Chilena de Anatomía 2020
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022020000601525
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Sumario:SUMMARY: The study reported the influence of the high and acute dose of Letrozole on the testis morphology in paca (Cuniculus paca), an aromatase inhibitor that reduces the endogenous estrogen, the essential hormone for spermatogenesis. Morphological changes were observed in seminiferous epithelium with germ cells with apoptotic characteristics and presence of vacuoles and nuclei in pycnose.