The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor

SUMMARY: The study reported the influence of the high and acute dose of Letrozole on the testis morphology in paca (Cuniculus paca), an aromatase inhibitor that reduces the endogenous estrogen, the essential hormone for spermatogenesis. Morphological changes were observed in seminiferous epithelium...

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Autores principales: Simões,Luciana Senna, Sasahara,Taís Harumi de Castro, Favaron,Phelipe Oliveira, Leal,Leonardo Martins, Oliveira,Fabrício Singaretti de, Fratini,Paula, Berger,Trish, Machado,Marcia Rita Fernandes, Miglino,Maria Angélica
Lenguaje:English
Publicado: Sociedad Chilena de Anatomía 2020
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022020000601525
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spelling oai:scielo:S0717-950220200006015252020-10-30The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase InhibitorSimões,Luciana SennaSasahara,Taís Harumi de CastroFavaron,Phelipe OliveiraLeal,Leonardo MartinsOliveira,Fabrício Singaretti deFratini,PaulaBerger,TrishMachado,Marcia Rita FernandesMiglino,Maria Angélica Gonadal Toxic Spermatogenesis SUMMARY: The study reported the influence of the high and acute dose of Letrozole on the testis morphology in paca (Cuniculus paca), an aromatase inhibitor that reduces the endogenous estrogen, the essential hormone for spermatogenesis. Morphological changes were observed in seminiferous epithelium with germ cells with apoptotic characteristics and presence of vacuoles and nuclei in pycnose.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.38 n.6 20202020-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022020000601525en10.4067/S0717-95022020000601525
institution Scielo Chile
collection Scielo Chile
language English
topic Gonadal
Toxic
Spermatogenesis
spellingShingle Gonadal
Toxic
Spermatogenesis
Simões,Luciana Senna
Sasahara,Taís Harumi de Castro
Favaron,Phelipe Oliveira
Leal,Leonardo Martins
Oliveira,Fabrício Singaretti de
Fratini,Paula
Berger,Trish
Machado,Marcia Rita Fernandes
Miglino,Maria Angélica
The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor
description SUMMARY: The study reported the influence of the high and acute dose of Letrozole on the testis morphology in paca (Cuniculus paca), an aromatase inhibitor that reduces the endogenous estrogen, the essential hormone for spermatogenesis. Morphological changes were observed in seminiferous epithelium with germ cells with apoptotic characteristics and presence of vacuoles and nuclei in pycnose.
author Simões,Luciana Senna
Sasahara,Taís Harumi de Castro
Favaron,Phelipe Oliveira
Leal,Leonardo Martins
Oliveira,Fabrício Singaretti de
Fratini,Paula
Berger,Trish
Machado,Marcia Rita Fernandes
Miglino,Maria Angélica
author_facet Simões,Luciana Senna
Sasahara,Taís Harumi de Castro
Favaron,Phelipe Oliveira
Leal,Leonardo Martins
Oliveira,Fabrício Singaretti de
Fratini,Paula
Berger,Trish
Machado,Marcia Rita Fernandes
Miglino,Maria Angélica
author_sort Simões,Luciana Senna
title The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor
title_short The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor
title_full The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor
title_fullStr The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor
title_full_unstemmed The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor
title_sort morphology of paca (cuniculus paca) testis with high dose of letrozole an aromatase inhibitor
publisher Sociedad Chilena de Anatomía
publishDate 2020
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022020000601525
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