Comparative Study on Erythrogram Parameters of Cell-Dyn Ruby and HumaCount 5L

SUMMARY: The use of hematological counts for the prevention, diagnosis and follow-up of hematological diseases has increased. Indeed, the correct operation of a clinical laboratory is essential to producing comparable results. However, there is a paucity of validation and reproducibility studies amo...

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Autores principales:	Carrasco,Camila, Carrasco,Danitza, Godoy,Karina, del Sol,Mariano, Sandoval,Cristian
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2020
Materias:	Cytology Epidemiology Flow Cytometry Hematology Public Health
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022020000601618
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spelling	oai:scielo:S0717-950220200006016182020-10-30Comparative Study on Erythrogram Parameters of Cell-Dyn Ruby and HumaCount 5LCarrasco,CamilaCarrasco,DanitzaGodoy,Karinadel Sol,MarianoSandoval,Cristian Cytology Epidemiology Flow Cytometry Hematology Public Health SUMMARY: The use of hematological counts for the prevention, diagnosis and follow-up of hematological diseases has increased. Indeed, the correct operation of a clinical laboratory is essential to producing comparable results. However, there is a paucity of validation and reproducibility studies among the different existing methods for clinical analysis. Therefore, our aim was to assess the commutability of the results provided by analyzers with different measuring systems. Sixty venous blood samples were obtained from patients, without discriminating for age or sex. Then, an automated hematological analysis was performed using the Cell-Dyn Ruby and HumaCount 5L instruments. The variables measured were: RBC, Hb, HCT, MCV, MCH and MCHC. The data were compared by a one-way ANOVA and Pearson’s correlation coefficient. Statistical significance was fixed at p < 0.05. There were no statistically significant differences for RBC, HCT, MCH or MCHC. In addition, with the exception of MCHC, all the analytes showed a good correlation coefficient between the two instruments. There is a variety of automated systems for the clinical laboratory and it is essential for the clinician to know the different methodologies used in hematological analyzers as well as their sensitivity and specificity. Therefore, our results are useful for demonstrating the importance of practical knowledge of the analyzers mentioned.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.38 n.6 20202020-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022020000601618en10.4067/S0717-95022020000601618
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Cytology Epidemiology Flow Cytometry Hematology Public Health
spellingShingle	Cytology Epidemiology Flow Cytometry Hematology Public Health Carrasco,Camila Carrasco,Danitza Godoy,Karina del Sol,Mariano Sandoval,Cristian Comparative Study on Erythrogram Parameters of Cell-Dyn Ruby and HumaCount 5L
description	SUMMARY: The use of hematological counts for the prevention, diagnosis and follow-up of hematological diseases has increased. Indeed, the correct operation of a clinical laboratory is essential to producing comparable results. However, there is a paucity of validation and reproducibility studies among the different existing methods for clinical analysis. Therefore, our aim was to assess the commutability of the results provided by analyzers with different measuring systems. Sixty venous blood samples were obtained from patients, without discriminating for age or sex. Then, an automated hematological analysis was performed using the Cell-Dyn Ruby and HumaCount 5L instruments. The variables measured were: RBC, Hb, HCT, MCV, MCH and MCHC. The data were compared by a one-way ANOVA and Pearson’s correlation coefficient. Statistical significance was fixed at p < 0.05. There were no statistically significant differences for RBC, HCT, MCH or MCHC. In addition, with the exception of MCHC, all the analytes showed a good correlation coefficient between the two instruments. There is a variety of automated systems for the clinical laboratory and it is essential for the clinician to know the different methodologies used in hematological analyzers as well as their sensitivity and specificity. Therefore, our results are useful for demonstrating the importance of practical knowledge of the analyzers mentioned.
author	Carrasco,Camila Carrasco,Danitza Godoy,Karina del Sol,Mariano Sandoval,Cristian
author_facet	Carrasco,Camila Carrasco,Danitza Godoy,Karina del Sol,Mariano Sandoval,Cristian
author_sort	Carrasco,Camila
title	Comparative Study on Erythrogram Parameters of Cell-Dyn Ruby and HumaCount 5L
title_short	Comparative Study on Erythrogram Parameters of Cell-Dyn Ruby and HumaCount 5L
title_full	Comparative Study on Erythrogram Parameters of Cell-Dyn Ruby and HumaCount 5L
title_fullStr	Comparative Study on Erythrogram Parameters of Cell-Dyn Ruby and HumaCount 5L
title_full_unstemmed	Comparative Study on Erythrogram Parameters of Cell-Dyn Ruby and HumaCount 5L
title_sort	comparative study on erythrogram parameters of cell-dyn ruby and humacount 5l
publisher	Sociedad Chilena de Anatomía
publishDate	2020
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022020000601618
work_keys_str_mv	AT carrascocamila comparativestudyonerythrogramparametersofcelldynrubyandhumacount5l AT carrascodanitza comparativestudyonerythrogramparametersofcelldynrubyandhumacount5l AT godoykarina comparativestudyonerythrogramparametersofcelldynrubyandhumacount5l AT delsolmariano comparativestudyonerythrogramparametersofcelldynrubyandhumacount5l AT sandovalcristian comparativestudyonerythrogramparametersofcelldynrubyandhumacount5l
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Comparative Study on Erythrogram Parameters of Cell-Dyn Ruby and HumaCount 5L

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