Preservation of Histology by Phenol-Based Fixative: Mini Review of Recent Findings

SUMMARY: In surgical and anatomical training, use of cadaver remains the most ideal technique. Standard formaldehyde solution preserves cadaveric tissues for an extended period comparing to the unfixed tissues. However, it fails to retain the natural texture, color, and biomechanical features. Pheno...

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Autores principales:	Rahman,S. M. Niazur, Alam,Tanbira, Alam,Nazmun Nahar
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2021
Materias:	Phenol Embalming solution Soft embalming Histological fixative Microscopy
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022021000100050
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spelling	oai:scielo:S0717-950220210001000502021-03-01Preservation of Histology by Phenol-Based Fixative: Mini Review of Recent FindingsRahman,S. M. NiazurAlam,TanbiraAlam,Nazmun Nahar Phenol Embalming solution Soft embalming Histological fixative Microscopy SUMMARY: In surgical and anatomical training, use of cadaver remains the most ideal technique. Standard formaldehyde solution preserves cadaveric tissues for an extended period comparing to the unfixed tissues. However, it fails to retain the natural texture, color, and biomechanical features. Phenol based soft embalming methods were developed to maintain these properties, while simultaneously decreasing the biohazard risk. Soft embalming techniques have made the bodies more ‘lifelike’ and wellfitted for training. Though phenol fixation displays rewarding morphological maintenance, we have scanty evidences on the histological preservation. This mini review primarily discussed the latest reports regarding the effect of phenol-based fixation on the tissue histology. Published literatures revealed phenol-based fixation displayed comparable histological preservation to that ofgold standard paraformaldehyde-based solution. It was concluded that phenol-based solution is an excellent fixative used to preserve tissues for microscopic analysis.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.39 n.1 20212021-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022021000100050en10.4067/S0717-95022021000100050
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Phenol Embalming solution Soft embalming Histological fixative Microscopy
spellingShingle	Phenol Embalming solution Soft embalming Histological fixative Microscopy Rahman,S. M. Niazur Alam,Tanbira Alam,Nazmun Nahar Preservation of Histology by Phenol-Based Fixative: Mini Review of Recent Findings
description	SUMMARY: In surgical and anatomical training, use of cadaver remains the most ideal technique. Standard formaldehyde solution preserves cadaveric tissues for an extended period comparing to the unfixed tissues. However, it fails to retain the natural texture, color, and biomechanical features. Phenol based soft embalming methods were developed to maintain these properties, while simultaneously decreasing the biohazard risk. Soft embalming techniques have made the bodies more ‘lifelike’ and wellfitted for training. Though phenol fixation displays rewarding morphological maintenance, we have scanty evidences on the histological preservation. This mini review primarily discussed the latest reports regarding the effect of phenol-based fixation on the tissue histology. Published literatures revealed phenol-based fixation displayed comparable histological preservation to that ofgold standard paraformaldehyde-based solution. It was concluded that phenol-based solution is an excellent fixative used to preserve tissues for microscopic analysis.
author	Rahman,S. M. Niazur Alam,Tanbira Alam,Nazmun Nahar
author_facet	Rahman,S. M. Niazur Alam,Tanbira Alam,Nazmun Nahar
author_sort	Rahman,S. M. Niazur
title	Preservation of Histology by Phenol-Based Fixative: Mini Review of Recent Findings
title_short	Preservation of Histology by Phenol-Based Fixative: Mini Review of Recent Findings
title_full	Preservation of Histology by Phenol-Based Fixative: Mini Review of Recent Findings
title_fullStr	Preservation of Histology by Phenol-Based Fixative: Mini Review of Recent Findings
title_full_unstemmed	Preservation of Histology by Phenol-Based Fixative: Mini Review of Recent Findings
title_sort	preservation of histology by phenol-based fixative: mini review of recent findings
publisher	Sociedad Chilena de Anatomía
publishDate	2021
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022021000100050
work_keys_str_mv	AT rahmansmniazur preservationofhistologybyphenolbasedfixativeminireviewofrecentfindings AT alamtanbira preservationofhistologybyphenolbasedfixativeminireviewofrecentfindings AT alamnazmunnahar preservationofhistologybyphenolbasedfixativeminireviewofrecentfindings
_version_	1718445179542700032

Preservation of Histology by Phenol-Based Fixative: Mini Review of Recent Findings

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