Cranial Bone Regeneration with Collagen Type I and Polyvinylpyrrolidone (Fibroquel®) Combined with Hyaluronic Acid in Wistar Rats: Morphological Study
SUMMARY: The purpose of this study was to evaluate by morphological methods, if a mixture of Fibroquel® and hyaluronic acid implanted in an animal model of cranial bone injury could promote bone regeneration. 12 Wistar rats were divided in three groups, control group, bone injury without treatment a...
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| Lenguaje: | English |
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Sociedad Chilena de Anatomía
2021
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oai:scielo:S0717-950220210003008162021-07-25Cranial Bone Regeneration with Collagen Type I and Polyvinylpyrrolidone (Fibroquel®) Combined with Hyaluronic Acid in Wistar Rats: Morphological StudySoto-Domínguez,AdolfoZatarain-Hernández,GilbertoGarcía-Garza,RubénNava-Rivera,Lydia EnithPietschmann-Santamaría,María de los ÁngelesDíaz-Palomares,EnriquePacheco-Herrera,Edson JosueLozoya-Martínez,RodrigoHolguin-Santana,María de la PazBetancourt-Martínez,Nadia DenysMillán-Orozco,JairMorán-Martínez,Javier Bone Cranial Regeneration Collagen Wistar Rat SUMMARY: The purpose of this study was to evaluate by morphological methods, if a mixture of Fibroquel® and hyaluronic acid implanted in an animal model of cranial bone injury could promote bone regeneration. 12 Wistar rats were divided in three groups, control group, bone injury without treatment and bone injury with treatment. After experimental period, bone samples were taken and stained with H & E, Masson trichrome, PAS-D, immunohistochemistry with anti-PCNA monoclonal antibody and applied a semiquantitative morphometric method. Treatment group showed extensive areas of collagen fibers in contact with normal bone tissue, areas of normal histology, PAS positive material and less cellular proliferation. We demonstrated for the first time that a mixture of Fibroquel® and hyaluronic acid implanted in an animal model of cranial bone injury promotes bone regeneration.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.39 n.3 20212021-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022021000300816en10.4067/S0717-95022021000300816 |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
English |
| topic |
Bone Cranial Regeneration Collagen Wistar Rat |
| spellingShingle |
Bone Cranial Regeneration Collagen Wistar Rat Soto-Domínguez,Adolfo Zatarain-Hernández,Gilberto García-Garza,Rubén Nava-Rivera,Lydia Enith Pietschmann-Santamaría,María de los Ángeles Díaz-Palomares,Enrique Pacheco-Herrera,Edson Josue Lozoya-Martínez,Rodrigo Holguin-Santana,María de la Paz Betancourt-Martínez,Nadia Denys Millán-Orozco,Jair Morán-Martínez,Javier Cranial Bone Regeneration with Collagen Type I and Polyvinylpyrrolidone (Fibroquel®) Combined with Hyaluronic Acid in Wistar Rats: Morphological Study |
| description |
SUMMARY: The purpose of this study was to evaluate by morphological methods, if a mixture of Fibroquel® and hyaluronic acid implanted in an animal model of cranial bone injury could promote bone regeneration. 12 Wistar rats were divided in three groups, control group, bone injury without treatment and bone injury with treatment. After experimental period, bone samples were taken and stained with H & E, Masson trichrome, PAS-D, immunohistochemistry with anti-PCNA monoclonal antibody and applied a semiquantitative morphometric method. Treatment group showed extensive areas of collagen fibers in contact with normal bone tissue, areas of normal histology, PAS positive material and less cellular proliferation. We demonstrated for the first time that a mixture of Fibroquel® and hyaluronic acid implanted in an animal model of cranial bone injury promotes bone regeneration. |
| author |
Soto-Domínguez,Adolfo Zatarain-Hernández,Gilberto García-Garza,Rubén Nava-Rivera,Lydia Enith Pietschmann-Santamaría,María de los Ángeles Díaz-Palomares,Enrique Pacheco-Herrera,Edson Josue Lozoya-Martínez,Rodrigo Holguin-Santana,María de la Paz Betancourt-Martínez,Nadia Denys Millán-Orozco,Jair Morán-Martínez,Javier |
| author_facet |
Soto-Domínguez,Adolfo Zatarain-Hernández,Gilberto García-Garza,Rubén Nava-Rivera,Lydia Enith Pietschmann-Santamaría,María de los Ángeles Díaz-Palomares,Enrique Pacheco-Herrera,Edson Josue Lozoya-Martínez,Rodrigo Holguin-Santana,María de la Paz Betancourt-Martínez,Nadia Denys Millán-Orozco,Jair Morán-Martínez,Javier |
| author_sort |
Soto-Domínguez,Adolfo |
| title |
Cranial Bone Regeneration with Collagen Type I and Polyvinylpyrrolidone (Fibroquel®) Combined with Hyaluronic Acid in Wistar Rats: Morphological Study |
| title_short |
Cranial Bone Regeneration with Collagen Type I and Polyvinylpyrrolidone (Fibroquel®) Combined with Hyaluronic Acid in Wistar Rats: Morphological Study |
| title_full |
Cranial Bone Regeneration with Collagen Type I and Polyvinylpyrrolidone (Fibroquel®) Combined with Hyaluronic Acid in Wistar Rats: Morphological Study |
| title_fullStr |
Cranial Bone Regeneration with Collagen Type I and Polyvinylpyrrolidone (Fibroquel®) Combined with Hyaluronic Acid in Wistar Rats: Morphological Study |
| title_full_unstemmed |
Cranial Bone Regeneration with Collagen Type I and Polyvinylpyrrolidone (Fibroquel®) Combined with Hyaluronic Acid in Wistar Rats: Morphological Study |
| title_sort |
cranial bone regeneration with collagen type i and polyvinylpyrrolidone (fibroquel®) combined with hyaluronic acid in wistar rats: morphological study |
| publisher |
Sociedad Chilena de Anatomía |
| publishDate |
2021 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022021000300816 |
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