Relationship Between Ethanol Intake and Insulin Sensitivity Metabolism in Men with no Comorbidities: A Systematic Review

SUMMARY: The association of alcohol consumption with type 2 diabetes has been explained by increased insulin sensitivity, anti-inflammatory effects, or effects of adiponectin. The aim was to launch a consistent relation between alcohol intake and insulin sensitivity. Several databases (MEDLINE, EMBA...

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Autores principales: Sandoval,Cristian, Herrera,Christian, Schulz,Mabel, Vásquez,Bélgica
Lenguaje:English
Publicado: Sociedad Chilena de Anatomía 2021
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022021000300829
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spelling oai:scielo:S0717-950220210003008292021-07-25Relationship Between Ethanol Intake and Insulin Sensitivity Metabolism in Men with no Comorbidities: A Systematic ReviewSandoval,CristianHerrera,ChristianSchulz,MabelVásquez,Bélgica Alcohol drinking Diabetes mellitus Epidemiology Insulin Humans SUMMARY: The association of alcohol consumption with type 2 diabetes has been explained by increased insulin sensitivity, anti-inflammatory effects, or effects of adiponectin. The aim was to launch a consistent relation between alcohol intake and insulin sensitivity. Several databases (MEDLINE, EMBASE, Scopus and Web of Science) were searched from 1990 to April 2020 for studies in English, using MeSH terms and text words involving to alcohol consumption and insulin sensitivity. Protocol registered on PROSPERO CRD42020205107. A total of seven original articles were analyzed, where four collected data through cross-sectional study, two papers with randomized crossover design, and one used a non-randomized study. The protective effect of moderate alcohol consumption on type 2 diabetes has been described, where an improvement on insulin levels has been shown in adults between 26.5-57 years old. Our research shows that alcohol effects on blood insulin levels could vary depending of the type of alcoholic drink ingested; and that alcohol intake increased leptin and adiponectin levels, suggesting that alcohol consumption may increase glucose catabolism promoting insulin sensitivity via leptin and adiponectin. However, original studies should consider time of exposure, age, dosage, ethnicity, and alcohol type in order to conclude right affirmations.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.39 n.3 20212021-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022021000300829en10.4067/S0717-95022021000300829
institution Scielo Chile
collection Scielo Chile
language English
topic Alcohol drinking
Diabetes mellitus
Epidemiology
Insulin
Humans
spellingShingle Alcohol drinking
Diabetes mellitus
Epidemiology
Insulin
Humans
Sandoval,Cristian
Herrera,Christian
Schulz,Mabel
Vásquez,Bélgica
Relationship Between Ethanol Intake and Insulin Sensitivity Metabolism in Men with no Comorbidities: A Systematic Review
description SUMMARY: The association of alcohol consumption with type 2 diabetes has been explained by increased insulin sensitivity, anti-inflammatory effects, or effects of adiponectin. The aim was to launch a consistent relation between alcohol intake and insulin sensitivity. Several databases (MEDLINE, EMBASE, Scopus and Web of Science) were searched from 1990 to April 2020 for studies in English, using MeSH terms and text words involving to alcohol consumption and insulin sensitivity. Protocol registered on PROSPERO CRD42020205107. A total of seven original articles were analyzed, where four collected data through cross-sectional study, two papers with randomized crossover design, and one used a non-randomized study. The protective effect of moderate alcohol consumption on type 2 diabetes has been described, where an improvement on insulin levels has been shown in adults between 26.5-57 years old. Our research shows that alcohol effects on blood insulin levels could vary depending of the type of alcoholic drink ingested; and that alcohol intake increased leptin and adiponectin levels, suggesting that alcohol consumption may increase glucose catabolism promoting insulin sensitivity via leptin and adiponectin. However, original studies should consider time of exposure, age, dosage, ethnicity, and alcohol type in order to conclude right affirmations.
author Sandoval,Cristian
Herrera,Christian
Schulz,Mabel
Vásquez,Bélgica
author_facet Sandoval,Cristian
Herrera,Christian
Schulz,Mabel
Vásquez,Bélgica
author_sort Sandoval,Cristian
title Relationship Between Ethanol Intake and Insulin Sensitivity Metabolism in Men with no Comorbidities: A Systematic Review
title_short Relationship Between Ethanol Intake and Insulin Sensitivity Metabolism in Men with no Comorbidities: A Systematic Review
title_full Relationship Between Ethanol Intake and Insulin Sensitivity Metabolism in Men with no Comorbidities: A Systematic Review
title_fullStr Relationship Between Ethanol Intake and Insulin Sensitivity Metabolism in Men with no Comorbidities: A Systematic Review
title_full_unstemmed Relationship Between Ethanol Intake and Insulin Sensitivity Metabolism in Men with no Comorbidities: A Systematic Review
title_sort relationship between ethanol intake and insulin sensitivity metabolism in men with no comorbidities: a systematic review
publisher Sociedad Chilena de Anatomía
publishDate 2021
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022021000300829
work_keys_str_mv AT sandovalcristian relationshipbetweenethanolintakeandinsulinsensitivitymetabolisminmenwithnocomorbiditiesasystematicreview
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AT schulzmabel relationshipbetweenethanolintakeandinsulinsensitivitymetabolisminmenwithnocomorbiditiesasystematicreview
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