Alveolar Bone Loss with Microarchitecture Changes in Aged Rat

SUMMARY: The aim of the present study was to evaluate the changes of alveolar bone in aged rats. The mandibles of the 4- month and 22-month aged rats were scanned by micro-CT. After the reconstruction of the alveolar bone,the distance between the cemento enamel junction (CEJ) and the alveolar bone c...

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Autores principales:	Zheng,Yong, Han,Nana
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2021
Materias:	Alveolar bone loss Mandible Micro-CT Bone histomorphometry
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022021000501443
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spelling	oai:scielo:S0717-950220210005014432021-10-19Alveolar Bone Loss with Microarchitecture Changes in Aged RatZheng,YongHan,Nana Alveolar bone loss Mandible Micro-CT Bone histomorphometry SUMMARY: The aim of the present study was to evaluate the changes of alveolar bone in aged rats. The mandibles of the 4- month and 22-month aged rats were scanned by micro-CT. After the reconstruction of the alveolar bone,the distance between the cemento enamel junction (CEJ) and the alveolar bone crest (ABC) was measured. The micro architectures of the inter-radicular alveolar bone were analyzed. The 22-month rats experienced the reduction in alveolar crest height in the buccal side and the lingual side, and significant increase in alveolar bone loss compared with the 4-month rats. The 22-month rats had a porous microarchitecture, the trabecular arrangement was obviously dissociated with the expanded inter-bone spaces of marrow, and the bone histomorphometry analysis showed the decreased bone volume/tissue volume and trabecular thickness in the 22-month rats. These results suggest that alveolar bone loss and alveolar trabecular bone deterioration might contribute to the weakening of molar support in the elderly.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.39 n.5 20212021-10-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022021000501443en10.4067/S0717-95022021000501443
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Alveolar bone loss Mandible Micro-CT Bone histomorphometry
spellingShingle	Alveolar bone loss Mandible Micro-CT Bone histomorphometry Zheng,Yong Han,Nana Alveolar Bone Loss with Microarchitecture Changes in Aged Rat
description	SUMMARY: The aim of the present study was to evaluate the changes of alveolar bone in aged rats. The mandibles of the 4- month and 22-month aged rats were scanned by micro-CT. After the reconstruction of the alveolar bone,the distance between the cemento enamel junction (CEJ) and the alveolar bone crest (ABC) was measured. The micro architectures of the inter-radicular alveolar bone were analyzed. The 22-month rats experienced the reduction in alveolar crest height in the buccal side and the lingual side, and significant increase in alveolar bone loss compared with the 4-month rats. The 22-month rats had a porous microarchitecture, the trabecular arrangement was obviously dissociated with the expanded inter-bone spaces of marrow, and the bone histomorphometry analysis showed the decreased bone volume/tissue volume and trabecular thickness in the 22-month rats. These results suggest that alveolar bone loss and alveolar trabecular bone deterioration might contribute to the weakening of molar support in the elderly.
author	Zheng,Yong Han,Nana
author_facet	Zheng,Yong Han,Nana
author_sort	Zheng,Yong
title	Alveolar Bone Loss with Microarchitecture Changes in Aged Rat
title_short	Alveolar Bone Loss with Microarchitecture Changes in Aged Rat
title_full	Alveolar Bone Loss with Microarchitecture Changes in Aged Rat
title_fullStr	Alveolar Bone Loss with Microarchitecture Changes in Aged Rat
title_full_unstemmed	Alveolar Bone Loss with Microarchitecture Changes in Aged Rat
title_sort	alveolar bone loss with microarchitecture changes in aged rat
publisher	Sociedad Chilena de Anatomía
publishDate	2021
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022021000501443
work_keys_str_mv	AT zhengyong alveolarbonelosswithmicroarchitecturechangesinagedrat AT hannana alveolarbonelosswithmicroarchitecturechangesinagedrat
_version_	1718445217975107584

Alveolar Bone Loss with Microarchitecture Changes in Aged Rat

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