CHEMICAL BASIS FOR THE ANTIMICROBIAL ACTIVITY OF ACETANILIDES

In vitro antimicrobial activity of a series of substituted acetanilides against S. aureus, E. coli and C. albicans were measured at two concentrations, 250 mug/ml and 500 mug/ml. Only the structures substituted with halogens in Calpha and electron acceptors in the aromatic ring are bioactive. The re...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Bravo,Hector R., Weiss-López,Boris, Lamborot,Madeleine, Copaja,Sylvia
Lenguaje:	English
Publicado:	Sociedad Chilena de Química 2003
Materias:	Acetanilides antimicrobial activity AM1-MO calculations
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072003000400005
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0717-97072003000400005
record_format	dspace
spelling	oai:scielo:S0717-970720030004000052004-04-26CHEMICAL BASIS FOR THE ANTIMICROBIAL ACTIVITY OF ACETANILIDESBravo,Hector R.Weiss-López,BorisLamborot,MadeleineCopaja,Sylvia Acetanilides antimicrobial activity AM1-MO calculations In vitro antimicrobial activity of a series of substituted acetanilides against S. aureus, E. coli and C. albicans were measured at two concentrations, 250 mug/ml and 500 mug/ml. Only the structures substituted with halogens in Calpha and electron acceptors in the aromatic ring are bioactive. The results are rationalized in terms of the acid properties of the N-H bond, as calculated using AM1-MO theoryinfo:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.48 n.4 20032003-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072003000400005en10.4067/S0717-97072003000400005
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Acetanilides antimicrobial activity AM1-MO calculations
spellingShingle	Acetanilides antimicrobial activity AM1-MO calculations Bravo,Hector R. Weiss-López,Boris Lamborot,Madeleine Copaja,Sylvia CHEMICAL BASIS FOR THE ANTIMICROBIAL ACTIVITY OF ACETANILIDES
description	In vitro antimicrobial activity of a series of substituted acetanilides against S. aureus, E. coli and C. albicans were measured at two concentrations, 250 mug/ml and 500 mug/ml. Only the structures substituted with halogens in Calpha and electron acceptors in the aromatic ring are bioactive. The results are rationalized in terms of the acid properties of the N-H bond, as calculated using AM1-MO theory
author	Bravo,Hector R. Weiss-López,Boris Lamborot,Madeleine Copaja,Sylvia
author_facet	Bravo,Hector R. Weiss-López,Boris Lamborot,Madeleine Copaja,Sylvia
author_sort	Bravo,Hector R.
title	CHEMICAL BASIS FOR THE ANTIMICROBIAL ACTIVITY OF ACETANILIDES
title_short	CHEMICAL BASIS FOR THE ANTIMICROBIAL ACTIVITY OF ACETANILIDES
title_full	CHEMICAL BASIS FOR THE ANTIMICROBIAL ACTIVITY OF ACETANILIDES
title_fullStr	CHEMICAL BASIS FOR THE ANTIMICROBIAL ACTIVITY OF ACETANILIDES
title_full_unstemmed	CHEMICAL BASIS FOR THE ANTIMICROBIAL ACTIVITY OF ACETANILIDES
title_sort	chemical basis for the antimicrobial activity of acetanilides
publisher	Sociedad Chilena de Química
publishDate	2003
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072003000400005
work_keys_str_mv	AT bravohectorr chemicalbasisfortheantimicrobialactivityofacetanilides AT weisslopezboris chemicalbasisfortheantimicrobialactivityofacetanilides AT lamborotmadeleine chemicalbasisfortheantimicrobialactivityofacetanilides AT copajasylvia chemicalbasisfortheantimicrobialactivityofacetanilides
_version_	1718445330232508416

CHEMICAL BASIS FOR THE ANTIMICROBIAL ACTIVITY OF ACETANILIDES

Ejemplares similares