USE OF ULTRAFILTRATION ON THE EVALUATION AND QUANTIFICATION OF THE INTERACTIONS BETWEEN POLYMERS AND LOW MOLECULAR-WEIGHT MOLECULES IN AQUEOUS SOLUTIONS

The theory and mathematical treatment of the evaluation of the interactions of water-soluble polymers with low molecular-weight molecules is presented. The interaction of the water-soluble polymer poly(sodium 4-styrenesulfonate) with L-tryptophan (Try), L-phenylalanine (Phe), chlorpheniramine maleat...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Moreno-Villoslada,Ignacio, Miranda,Víctor, Oyarzún,Felipe, Hess,Susan, Luna,Maribel, Rivas,Bernabé L.
Lenguaje:	English
Publicado:	Sociedad Chilena de Química 2004
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072004000200003
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0717-97072004000200003
record_format	dspace
spelling	oai:scielo:S0717-970720040002000032005-09-21USE OF ULTRAFILTRATION ON THE EVALUATION AND QUANTIFICATION OF THE INTERACTIONS BETWEEN POLYMERS AND LOW MOLECULAR-WEIGHT MOLECULES IN AQUEOUS SOLUTIONSMoreno-Villoslada,IgnacioMiranda,VíctorOyarzún,FelipeHess,SusanLuna,MaribelRivas,Bernabé L.The theory and mathematical treatment of the evaluation of the interactions of water-soluble polymers with low molecular-weight molecules is presented. The interaction of the water-soluble polymer poly(sodium 4-styrenesulfonate) with L-tryptophan (Try), L-phenylalanine (Phe), chlorpheniramine maleate (CPM), and 2,3,5-triphenyl-2H-tetrazolium chloride (TTC) is studied by this technique. Ultrafiltration experiments at pH 7.5, and different ionic strength values show weak interactions of the low molecular weight molecules TTC and CPM with the polymer with apparent dissociation constants of 0.26 and 0.32 respectively in the absence of NaNO3, and 2.02 and 1.2 in the presence of 0.10 of NaNO3 and 0.13 M of NaCl respectively. Negligible interactions are found for Try or Phe at pHs ranging between 4 and 10 and NaNO3 concentrations ranging between 0.0 and 0.15 M. This suggests that the interactions are mainly due to both long-range electrostatic forces and short-range interactions that may include hydrophobic forces or charge transfer complexation. The interaction of TTC with PSS in the absence of NaNO3 is reflected in UV-Vis spectroscopic studies by a decrease on the intensity of the maximum at 248 nminfo:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.49 n.2 20042004-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072004000200003en10.4067/S0717-97072004000200003
institution	Scielo Chile
collection	Scielo Chile
language	English
description	The theory and mathematical treatment of the evaluation of the interactions of water-soluble polymers with low molecular-weight molecules is presented. The interaction of the water-soluble polymer poly(sodium 4-styrenesulfonate) with L-tryptophan (Try), L-phenylalanine (Phe), chlorpheniramine maleate (CPM), and 2,3,5-triphenyl-2H-tetrazolium chloride (TTC) is studied by this technique. Ultrafiltration experiments at pH 7.5, and different ionic strength values show weak interactions of the low molecular weight molecules TTC and CPM with the polymer with apparent dissociation constants of 0.26 and 0.32 respectively in the absence of NaNO3, and 2.02 and 1.2 in the presence of 0.10 of NaNO3 and 0.13 M of NaCl respectively. Negligible interactions are found for Try or Phe at pHs ranging between 4 and 10 and NaNO3 concentrations ranging between 0.0 and 0.15 M. This suggests that the interactions are mainly due to both long-range electrostatic forces and short-range interactions that may include hydrophobic forces or charge transfer complexation. The interaction of TTC with PSS in the absence of NaNO3 is reflected in UV-Vis spectroscopic studies by a decrease on the intensity of the maximum at 248 nm
author	Moreno-Villoslada,Ignacio Miranda,Víctor Oyarzún,Felipe Hess,Susan Luna,Maribel Rivas,Bernabé L.
spellingShingle	Moreno-Villoslada,Ignacio Miranda,Víctor Oyarzún,Felipe Hess,Susan Luna,Maribel Rivas,Bernabé L. USE OF ULTRAFILTRATION ON THE EVALUATION AND QUANTIFICATION OF THE INTERACTIONS BETWEEN POLYMERS AND LOW MOLECULAR-WEIGHT MOLECULES IN AQUEOUS SOLUTIONS
author_facet	Moreno-Villoslada,Ignacio Miranda,Víctor Oyarzún,Felipe Hess,Susan Luna,Maribel Rivas,Bernabé L.
author_sort	Moreno-Villoslada,Ignacio
title	USE OF ULTRAFILTRATION ON THE EVALUATION AND QUANTIFICATION OF THE INTERACTIONS BETWEEN POLYMERS AND LOW MOLECULAR-WEIGHT MOLECULES IN AQUEOUS SOLUTIONS
title_short	USE OF ULTRAFILTRATION ON THE EVALUATION AND QUANTIFICATION OF THE INTERACTIONS BETWEEN POLYMERS AND LOW MOLECULAR-WEIGHT MOLECULES IN AQUEOUS SOLUTIONS
title_full	USE OF ULTRAFILTRATION ON THE EVALUATION AND QUANTIFICATION OF THE INTERACTIONS BETWEEN POLYMERS AND LOW MOLECULAR-WEIGHT MOLECULES IN AQUEOUS SOLUTIONS
title_fullStr	USE OF ULTRAFILTRATION ON THE EVALUATION AND QUANTIFICATION OF THE INTERACTIONS BETWEEN POLYMERS AND LOW MOLECULAR-WEIGHT MOLECULES IN AQUEOUS SOLUTIONS
title_full_unstemmed	USE OF ULTRAFILTRATION ON THE EVALUATION AND QUANTIFICATION OF THE INTERACTIONS BETWEEN POLYMERS AND LOW MOLECULAR-WEIGHT MOLECULES IN AQUEOUS SOLUTIONS
title_sort	use of ultrafiltration on the evaluation and quantification of the interactions between polymers and low molecular-weight molecules in aqueous solutions
publisher	Sociedad Chilena de Química
publishDate	2004
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072004000200003
work_keys_str_mv	AT morenovillosladaignacio useofultrafiltrationontheevaluationandquantificationoftheinteractionsbetweenpolymersandlowmolecularweightmoleculesinaqueoussolutions AT mirandavictor useofultrafiltrationontheevaluationandquantificationoftheinteractionsbetweenpolymersandlowmolecularweightmoleculesinaqueoussolutions AT oyarzunfelipe useofultrafiltrationontheevaluationandquantificationoftheinteractionsbetweenpolymersandlowmolecularweightmoleculesinaqueoussolutions AT hesssusan useofultrafiltrationontheevaluationandquantificationoftheinteractionsbetweenpolymersandlowmolecularweightmoleculesinaqueoussolutions AT lunamaribel useofultrafiltrationontheevaluationandquantificationoftheinteractionsbetweenpolymersandlowmolecularweightmoleculesinaqueoussolutions AT rivasbernabel useofultrafiltrationontheevaluationandquantificationoftheinteractionsbetweenpolymersandlowmolecularweightmoleculesinaqueoussolutions
_version_	1718445336988483584

USE OF ULTRAFILTRATION ON THE EVALUATION AND QUANTIFICATION OF THE INTERACTIONS BETWEEN POLYMERS AND LOW MOLECULAR-WEIGHT MOLECULES IN AQUEOUS SOLUTIONS

Ejemplares similares