ANTIBACTERIAL AND ANTIFUNGAL TERPENES FROM Pilgerodendron uviferum (D. DON) FLORIN
Ten sesquiterpenes (a-cubebene, copaene, alpha-caryophyllene, caryophyllene-4,5-epoxide, delta-cadinene, cubenol, epicubenol, torreyol, humulene-1,2-epoxide, 15-copaenol) and six diterpenes (hinokione, hinokiol, ferruginol, 6,7-dehydroferruginol, totarol, sugiol) were isolated and identified from Pi...
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Sociedad Chilena de Química
2004
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oai:scielo:S0717-970720040002000102005-09-21ANTIBACTERIAL AND ANTIFUNGAL TERPENES FROM Pilgerodendron uviferum (D. DON) FLORINSolís,C.Becerra,J.Flores,C.Robledo,J.Silva,M.Ten sesquiterpenes (a-cubebene, copaene, alpha-caryophyllene, caryophyllene-4,5-epoxide, delta-cadinene, cubenol, epicubenol, torreyol, humulene-1,2-epoxide, 15-copaenol) and six diterpenes (hinokione, hinokiol, ferruginol, 6,7-dehydroferruginol, totarol, sugiol) were isolated and identified from Pilgerodendron uviferum (D. Don) Florin wood and bark. The molecular structures were elucidated by spectroscopic methods. Twelve pure compounds were tested for antimicrobial activity against standard bacterial (Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aureginosa, Streptococcus pyogenes) and fungal strains (Ophiostoma piliferum, Rhizoctonia solani, Phragmidium violaceum, Fusarium graminearum, Pythium irregulare, Botrytis cinerea, Schizophyllum commune), as were crude total extracts, n-hexane, dichloromethane, and ethyl acetate partial extracts. All the compounds tested exhibited biological activity, with the most active being ferruginol, hinokiol, 15-copaenol, cubenol, torreyol, and n-hexane wood extracts and ethyl acetate bark extractinfo:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.49 n.2 20042004-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072004000200010en10.4067/S0717-97072004000200010 |
institution |
Scielo Chile |
collection |
Scielo Chile |
language |
English |
description |
Ten sesquiterpenes (a-cubebene, copaene, alpha-caryophyllene, caryophyllene-4,5-epoxide, delta-cadinene, cubenol, epicubenol, torreyol, humulene-1,2-epoxide, 15-copaenol) and six diterpenes (hinokione, hinokiol, ferruginol, 6,7-dehydroferruginol, totarol, sugiol) were isolated and identified from Pilgerodendron uviferum (D. Don) Florin wood and bark. The molecular structures were elucidated by spectroscopic methods. Twelve pure compounds were tested for antimicrobial activity against standard bacterial (Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aureginosa, Streptococcus pyogenes) and fungal strains (Ophiostoma piliferum, Rhizoctonia solani, Phragmidium violaceum, Fusarium graminearum, Pythium irregulare, Botrytis cinerea, Schizophyllum commune), as were crude total extracts, n-hexane, dichloromethane, and ethyl acetate partial extracts. All the compounds tested exhibited biological activity, with the most active being ferruginol, hinokiol, 15-copaenol, cubenol, torreyol, and n-hexane wood extracts and ethyl acetate bark extract |
author |
Solís,C. Becerra,J. Flores,C. Robledo,J. Silva,M. |
spellingShingle |
Solís,C. Becerra,J. Flores,C. Robledo,J. Silva,M. ANTIBACTERIAL AND ANTIFUNGAL TERPENES FROM Pilgerodendron uviferum (D. DON) FLORIN |
author_facet |
Solís,C. Becerra,J. Flores,C. Robledo,J. Silva,M. |
author_sort |
Solís,C. |
title |
ANTIBACTERIAL AND ANTIFUNGAL TERPENES FROM Pilgerodendron uviferum (D. DON) FLORIN |
title_short |
ANTIBACTERIAL AND ANTIFUNGAL TERPENES FROM Pilgerodendron uviferum (D. DON) FLORIN |
title_full |
ANTIBACTERIAL AND ANTIFUNGAL TERPENES FROM Pilgerodendron uviferum (D. DON) FLORIN |
title_fullStr |
ANTIBACTERIAL AND ANTIFUNGAL TERPENES FROM Pilgerodendron uviferum (D. DON) FLORIN |
title_full_unstemmed |
ANTIBACTERIAL AND ANTIFUNGAL TERPENES FROM Pilgerodendron uviferum (D. DON) FLORIN |
title_sort |
antibacterial and antifungal terpenes from pilgerodendron uviferum (d. don) florin |
publisher |
Sociedad Chilena de Química |
publishDate |
2004 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072004000200010 |
work_keys_str_mv |
AT solisc antibacterialandantifungalterpenesfrompilgerodendronuviferumddonflorin AT becerraj antibacterialandantifungalterpenesfrompilgerodendronuviferumddonflorin AT floresc antibacterialandantifungalterpenesfrompilgerodendronuviferumddonflorin AT robledoj antibacterialandantifungalterpenesfrompilgerodendronuviferumddonflorin AT silvam antibacterialandantifungalterpenesfrompilgerodendronuviferumddonflorin |
_version_ |
1718445338278232064 |