Synthesis and antibacterial activity of cefotaxime metal complexes
Cefotaxime (Hcefotax) interacts with transition metal ions to give [M(cefotax)Cl] complexes (M = Mn(II), Fe(III), Co(II), Ni(II), Cu(II) and Cd(II)) which were characterized by physicochemical and spectroscopic methods and a tetrahedral geometry is suggested for their structure. The IR and the ¹H-NM...
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Sociedad Chilena de Química
2005
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oai:scielo:S0717-970720050002000012005-07-19Synthesis and antibacterial activity of cefotaxime metal complexesAnacona,J.R.Silva,Gladys DaCefotaxime (Hcefotax) interacts with transition metal ions to give [M(cefotax)Cl] complexes (M = Mn(II), Fe(III), Co(II), Ni(II), Cu(II) and Cd(II)) which were characterized by physicochemical and spectroscopic methods and a tetrahedral geometry is suggested for their structure. The IR and the ¹H-NMR spectra of the complexes suggest that the cefotaxime behaves as monoanionic tridentate ligand . The complexes have been screened for antibacterial activity against several bacteria, and the results are compared with the activity of cefotaximeinfo:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.50 n.2 20052005-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072005000200001en10.4067/S0717-97072005000200001 |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
English |
| description |
Cefotaxime (Hcefotax) interacts with transition metal ions to give [M(cefotax)Cl] complexes (M = Mn(II), Fe(III), Co(II), Ni(II), Cu(II) and Cd(II)) which were characterized by physicochemical and spectroscopic methods and a tetrahedral geometry is suggested for their structure. The IR and the ¹H-NMR spectra of the complexes suggest that the cefotaxime behaves as monoanionic tridentate ligand . The complexes have been screened for antibacterial activity against several bacteria, and the results are compared with the activity of cefotaxime |
| author |
Anacona,J.R. Silva,Gladys Da |
| spellingShingle |
Anacona,J.R. Silva,Gladys Da Synthesis and antibacterial activity of cefotaxime metal complexes |
| author_facet |
Anacona,J.R. Silva,Gladys Da |
| author_sort |
Anacona,J.R. |
| title |
Synthesis and antibacterial activity of cefotaxime metal complexes |
| title_short |
Synthesis and antibacterial activity of cefotaxime metal complexes |
| title_full |
Synthesis and antibacterial activity of cefotaxime metal complexes |
| title_fullStr |
Synthesis and antibacterial activity of cefotaxime metal complexes |
| title_full_unstemmed |
Synthesis and antibacterial activity of cefotaxime metal complexes |
| title_sort |
synthesis and antibacterial activity of cefotaxime metal complexes |
| publisher |
Sociedad Chilena de Química |
| publishDate |
2005 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072005000200001 |
| work_keys_str_mv |
AT anaconajr synthesisandantibacterialactivityofcefotaximemetalcomplexes AT silvagladysda synthesisandantibacterialactivityofcefotaximemetalcomplexes |
| _version_ |
1718445347679764480 |