METHOD VALIDATION FOR THE DETERMINATION OF FUROSEMIDE IN PLASMA BY LIQUID- LIQUID EXTRACTION AND HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY WITH FLUORESCENCE DETECTION

A practical reversed-phase high-performance liquid chromatography (HPLC) method was developed for 4-chloro-N-furfuryl-5-sulphamoylanthranilic acid (furosemide) determination in plasma. The plasma samples spiked with the drug in presence of propranolol hydrochloride as internal standard, were purifie...

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Autores principales: GOMEZ G,CAROLINA, PLESSING R,CARLOS von, GODOY M,C. GLORIA, REINBACH H,ROLANDO, GODOY R,RICARDO
Lenguaje:English
Publicado: Sociedad Chilena de Química 2005
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072005000200008
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