SYNTHESIS OF 2-ARYL-1,3-PROPANEDIAMINES USING A ONE-POT KNOEVENAGEL-MICHAEL SEQUENCE

A simple synthetic route for the preparation of 2-phenyl-1,3-propanediamines, based on a Knoevenagel-Michael double condensation followed by reduction, was developed using nitromethane as reagent and solvent, and sodium bicarbonate as base in the first step, followed by catalytic hydrogenation over...

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Autores principales: ITURRIAGA-VÁSQUEZ,PATRICIO, LÜHR-SIERRA,SUSAN, CAROLI REZENDE,MARCOS, CASSELS,BRUCE K
Lenguaje:English
Publicado: Sociedad Chilena de Química 2006
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072006000100006
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spelling oai:scielo:S0717-970720060001000062006-06-08SYNTHESIS OF 2-ARYL-1,3-PROPANEDIAMINES USING A ONE-POT KNOEVENAGEL-MICHAEL SEQUENCEITURRIAGA-VÁSQUEZ,PATRICIOLÜHR-SIERRA,SUSANCAROLI REZENDE,MARCOSCASSELS,BRUCE K Knoevenagel-Michael double condensation 2-phenyl-1,3-propanediamines catalytic hydrogenation Adams catalyst A simple synthetic route for the preparation of 2-phenyl-1,3-propanediamines, based on a Knoevenagel-Michael double condensation followed by reduction, was developed using nitromethane as reagent and solvent, and sodium bicarbonate as base in the first step, followed by catalytic hydrogenation over Adams catalystinfo:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.51 n.1 20062006-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072006000100006en10.4067/S0717-97072006000100006
institution Scielo Chile
collection Scielo Chile
language English
topic Knoevenagel-Michael double condensation
2-phenyl-1,3-propanediamines
catalytic hydrogenation
Adams catalyst
spellingShingle Knoevenagel-Michael double condensation
2-phenyl-1,3-propanediamines
catalytic hydrogenation
Adams catalyst
ITURRIAGA-VÁSQUEZ,PATRICIO
LÜHR-SIERRA,SUSAN
CAROLI REZENDE,MARCOS
CASSELS,BRUCE K
SYNTHESIS OF 2-ARYL-1,3-PROPANEDIAMINES USING A ONE-POT KNOEVENAGEL-MICHAEL SEQUENCE
description A simple synthetic route for the preparation of 2-phenyl-1,3-propanediamines, based on a Knoevenagel-Michael double condensation followed by reduction, was developed using nitromethane as reagent and solvent, and sodium bicarbonate as base in the first step, followed by catalytic hydrogenation over Adams catalyst
author ITURRIAGA-VÁSQUEZ,PATRICIO
LÜHR-SIERRA,SUSAN
CAROLI REZENDE,MARCOS
CASSELS,BRUCE K
author_facet ITURRIAGA-VÁSQUEZ,PATRICIO
LÜHR-SIERRA,SUSAN
CAROLI REZENDE,MARCOS
CASSELS,BRUCE K
author_sort ITURRIAGA-VÁSQUEZ,PATRICIO
title SYNTHESIS OF 2-ARYL-1,3-PROPANEDIAMINES USING A ONE-POT KNOEVENAGEL-MICHAEL SEQUENCE
title_short SYNTHESIS OF 2-ARYL-1,3-PROPANEDIAMINES USING A ONE-POT KNOEVENAGEL-MICHAEL SEQUENCE
title_full SYNTHESIS OF 2-ARYL-1,3-PROPANEDIAMINES USING A ONE-POT KNOEVENAGEL-MICHAEL SEQUENCE
title_fullStr SYNTHESIS OF 2-ARYL-1,3-PROPANEDIAMINES USING A ONE-POT KNOEVENAGEL-MICHAEL SEQUENCE
title_full_unstemmed SYNTHESIS OF 2-ARYL-1,3-PROPANEDIAMINES USING A ONE-POT KNOEVENAGEL-MICHAEL SEQUENCE
title_sort synthesis of 2-aryl-1,3-propanediamines using a one-pot knoevenagel-michael sequence
publisher Sociedad Chilena de Química
publishDate 2006
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072006000100006
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