SYNTHESIS OF 2-ARYL-1,3-PROPANEDIAMINES USING A ONE-POT KNOEVENAGEL-MICHAEL SEQUENCE

A simple synthetic route for the preparation of 2-phenyl-1,3-propanediamines, based on a Knoevenagel-Michael double condensation followed by reduction, was developed using nitromethane as reagent and solvent, and sodium bicarbonate as base in the first step, followed by catalytic hydrogenation over...

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Autores principales: ITURRIAGA-VÁSQUEZ,PATRICIO, LÜHR-SIERRA,SUSAN, CAROLI REZENDE,MARCOS, CASSELS,BRUCE K
Lenguaje:English
Publicado: Sociedad Chilena de Química 2006
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072006000100006
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