SYNTHESIS AND STRUCTURAL CHARACTERIZATION OF N-BENZOYL-TRYPTAMINE AND ITS NEW ANALOGUE N-SALICYLOYLTRYPTAMINE, A POTENTIAL ANTICONVULSANT AGENT

N-Benzoyltryptamine (3), previously isolated from Myrtopsis myrtoidea and a new analogue, N-salicyloyltryptamine (5), were prepared by coupling tryptamine with benzoylchloride and methyl salicylate, respectively. Their structural elucidation was made by the usual spectroscopic methods and two-diment...

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Autores principales:	ASSIS OLIVEIRA,FRANCISCO DE, ANTAS E SILVA,DAVI, QUINTANS-JÚNIOR,LUCINDO JOSÉ, CHAVEZ GUTIERREZ,STANLEY JUAN, NÓBREGA DE ALMEIDA,REINALDO, BARBOSA-FILHO,JOSÉ MARIA, VANDERLEI DE SOUZA,MARIA DE FÁTIMA
Lenguaje:	English
Publicado:	Sociedad Chilena de Química 2006
Materias:	N-benzoyltryptamine N-salicyloyltryptamine two-dimentional NMR spectroscopy anti-convulsant activity
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072006000200016
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spelling	oai:scielo:S0717-970720060002000162006-06-30SYNTHESIS AND STRUCTURAL CHARACTERIZATION OF N-BENZOYL-TRYPTAMINE AND ITS NEW ANALOGUE N-SALICYLOYLTRYPTAMINE, A POTENTIAL ANTICONVULSANT AGENTASSIS OLIVEIRA,FRANCISCO DEANTAS E SILVA,DAVIQUINTANS-JÚNIOR,LUCINDO JOSÉCHAVEZ GUTIERREZ,STANLEY JUANNÓBREGA DE ALMEIDA,REINALDOBARBOSA-FILHO,JOSÉ MARIAVANDERLEI DE SOUZA,MARIA DE FÁTIMA N-benzoyltryptamine N-salicyloyltryptamine two-dimentional NMR spectroscopy anti-convulsant activity N-Benzoyltryptamine (3), previously isolated from Myrtopsis myrtoidea and a new analogue, N-salicyloyltryptamine (5), were prepared by coupling tryptamine with benzoylchloride and methyl salicylate, respectively. Their structural elucidation was made by the usual spectroscopic methods and two-dimentional NMR techniques COSY, COBY and HMBC. N-salicyloyltryptamine (5) was submitted to pharmacological screening behavior, showing depressant effectsinfo:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.51 n.2 20062006-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072006000200016en10.4067/S0717-97072006000200016
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	N-benzoyltryptamine N-salicyloyltryptamine two-dimentional NMR spectroscopy anti-convulsant activity
spellingShingle	N-benzoyltryptamine N-salicyloyltryptamine two-dimentional NMR spectroscopy anti-convulsant activity ASSIS OLIVEIRA,FRANCISCO DE ANTAS E SILVA,DAVI QUINTANS-JÚNIOR,LUCINDO JOSÉ CHAVEZ GUTIERREZ,STANLEY JUAN NÓBREGA DE ALMEIDA,REINALDO BARBOSA-FILHO,JOSÉ MARIA VANDERLEI DE SOUZA,MARIA DE FÁTIMA SYNTHESIS AND STRUCTURAL CHARACTERIZATION OF N-BENZOYL-TRYPTAMINE AND ITS NEW ANALOGUE N-SALICYLOYLTRYPTAMINE, A POTENTIAL ANTICONVULSANT AGENT
description	N-Benzoyltryptamine (3), previously isolated from Myrtopsis myrtoidea and a new analogue, N-salicyloyltryptamine (5), were prepared by coupling tryptamine with benzoylchloride and methyl salicylate, respectively. Their structural elucidation was made by the usual spectroscopic methods and two-dimentional NMR techniques COSY, COBY and HMBC. N-salicyloyltryptamine (5) was submitted to pharmacological screening behavior, showing depressant effects
author	ASSIS OLIVEIRA,FRANCISCO DE ANTAS E SILVA,DAVI QUINTANS-JÚNIOR,LUCINDO JOSÉ CHAVEZ GUTIERREZ,STANLEY JUAN NÓBREGA DE ALMEIDA,REINALDO BARBOSA-FILHO,JOSÉ MARIA VANDERLEI DE SOUZA,MARIA DE FÁTIMA
author_facet	ASSIS OLIVEIRA,FRANCISCO DE ANTAS E SILVA,DAVI QUINTANS-JÚNIOR,LUCINDO JOSÉ CHAVEZ GUTIERREZ,STANLEY JUAN NÓBREGA DE ALMEIDA,REINALDO BARBOSA-FILHO,JOSÉ MARIA VANDERLEI DE SOUZA,MARIA DE FÁTIMA
author_sort	ASSIS OLIVEIRA,FRANCISCO DE
title	SYNTHESIS AND STRUCTURAL CHARACTERIZATION OF N-BENZOYL-TRYPTAMINE AND ITS NEW ANALOGUE N-SALICYLOYLTRYPTAMINE, A POTENTIAL ANTICONVULSANT AGENT
title_short	SYNTHESIS AND STRUCTURAL CHARACTERIZATION OF N-BENZOYL-TRYPTAMINE AND ITS NEW ANALOGUE N-SALICYLOYLTRYPTAMINE, A POTENTIAL ANTICONVULSANT AGENT
title_full	SYNTHESIS AND STRUCTURAL CHARACTERIZATION OF N-BENZOYL-TRYPTAMINE AND ITS NEW ANALOGUE N-SALICYLOYLTRYPTAMINE, A POTENTIAL ANTICONVULSANT AGENT
title_fullStr	SYNTHESIS AND STRUCTURAL CHARACTERIZATION OF N-BENZOYL-TRYPTAMINE AND ITS NEW ANALOGUE N-SALICYLOYLTRYPTAMINE, A POTENTIAL ANTICONVULSANT AGENT
title_full_unstemmed	SYNTHESIS AND STRUCTURAL CHARACTERIZATION OF N-BENZOYL-TRYPTAMINE AND ITS NEW ANALOGUE N-SALICYLOYLTRYPTAMINE, A POTENTIAL ANTICONVULSANT AGENT
title_sort	synthesis and structural characterization of n-benzoyl-tryptamine and its new analogue n-salicyloyltryptamine, a potential anticonvulsant agent
publisher	Sociedad Chilena de Química
publishDate	2006
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072006000200016
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SYNTHESIS AND STRUCTURAL CHARACTERIZATION OF N-BENZOYL-TRYPTAMINE AND ITS NEW ANALOGUE N-SALICYLOYLTRYPTAMINE, A POTENTIAL ANTICONVULSANT AGENT

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