N-SUBSTITUTION AND á1-ADRENERGIC RECEPTOR AFFINITY OF LAUDANOSINE ANALOGUES

N-SUBSTITUTION AND á1-ADRENERGIC RECEPTOR AFFINITY OF LAUDANOSINE ANALOGUES

Benzyltetrahydroisoquinoline (BTHIQ) molecules are able to adopt widely differing conformations that depend on the presence or absence of N-substituents. To assess the possible role of BTHIQ conformation on the affinity of these compounds for a 1-adrenergic receptors, of interest for the management...

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Autores principales: ITURRIAGA-VÁSQUEZ,PATRICIO, CASSELS,BRUCE K, IVORRA,M. DOLORES, D'OCON,M. PILAR
Lenguaje:English
Publicado: Sociedad Chilena de Química 2006
Materias:
a 1-adrenergic receptor binding
norlaudanosine
laudanosine
N-alkylnorlaudanosines
benzyltetrahydroisoquinolines
tetrahydropalmatine
glaucine
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072006000300001
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http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072006000300001

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