HYDROPHOBICALLY MODIFIED POLYELECTROLYTES AS POTENTIAL DRUGS RESERVOIRS OF N-ALKYL-NITROIMIDAZOLES

The solubilization of three commercial drugs (ornindazole, metronidazole and tinidazole) and model compounds (N-alkyl-2-methyl-4-nitroimidazoles) on aggregates formed by anionic polyelectrolytes, carrying alkyl side chains of different length, have been investigated in aqueous solution at pH 3.0, 7....

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Autores principales: SALAMANCA,CONSTAIN H, BARRAZA,RAÚL G, ACEVEDO,BETSABÉ, OLEA,ANDRÉS F
Lenguaje:English
Publicado: Sociedad Chilena de Química 2007
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072007000100014
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