SYNTHESIS OF NOVEL PYRAZOLE, COUMARIN AND PYRIDAZINE DERIVATIVES EVALUATED AS POTENTIAL ANTIMICROBIAL AND ANTIFUNGAL AGENTS

SYNTHESIS OF NOVEL PYRAZOLE, COUMARIN AND PYRIDAZINE DERIVATIVES EVALUATED AS POTENTIAL ANTIMICROBIAL AND ANTIFUNGAL AGENTS

The reaction of cyanoacetylhydrazine with ω-bromoacetophenone gave the N’-[2-bromo-1-phenylethylidene]-2-isocyanoacetohydrazide (3). The latter compound underwent ready cyclization when treated with potassium cyanide to give the 1-(isocyanoacetyl)-3-phenyl-1H-pyrazol-5-amine (6). Compound 6...

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Autores principales: WARDAKHAN,WAGNAT W, LOUCA,NADIA A
Lenguaje:English
Publicado: Sociedad Chilena de Química 2007
Materias:
Cyanoacetylhydrazine
Pyrazole
Coumarin
Pyridazine
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072007000200006
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