A THEORETICAL STUDY OF THE INHIBITION OF WILD-TYPE AND DRUG-RESISTANT HTV-1 REVERSE TRANSCRIPTASE BY SOME THIAZOLIDENEBENZENESULFONAMIDE DERIVATIVES

We present the results of a quantum chemical study of the relationship between the electronic-conformational structure of a group of thiazolidenebenzenesulfo namide derivatives (TBS) and their Immunodeficiency Type 1 Virus (HTV-1) Reverse Transcriptase (RT, the wild one and two mutated types) inhibi...

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Bibliographic Details
Main Authors: SOTO-MORALES,FRANCISCO, GÓMEZ-JERIA,JUAN S
Language:English
Published: Sociedad Chilena de Química 2007
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Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072007000300004
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