1-BENZOYL-2-(2-NITROPHENYL)-1H-BENZIMIDAZOLE DERIVATIVES: A NOVEL APPROACH TO THE DEVELOPMENT OF NEW HIV-1 REVERSE TRANSCRIPTASE INHIBITORS

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1-BENZOYL-2-(2-NITROPHENYL)-1H-BENZIMIDAZOLE DERIVATIVES: A NOVEL APPROACH TO THE DEVELOPMENT OF NEW HIV-1 REVERSE TRANSCRIPTASE INHIBITORS

A novel approach to the development of a new class of HIV-1 RT inhibitors is reported. The 1-benzoyl-2-aryl-1H-benzimidazole series was designed as a combination of two previously reported active scaffolds, the benzimidazole and benzoyl moieties. The active compounds of the series effectively blocke...

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Detalles Bibliográficos
Autores principales:	VÁSQUEZ,DAVID, LAGOS,CARLOS F, MELLA-RAIPÁN,JAIME, GONZÁLEZ,LUIS, EBENSPERGER,ROBERTO, ALVAREZ-FIGUEROA,M. JAVIERA, SÁEZ,EDMUNDO, PESSOA-MAHANA,HERNÁN, ARAYA-SECCHP,RAÚL, GONZÁLEZ-WONG,ANGEL, PÉREZ-ACLE,TOMÁS, PESSOA-MAHANA,C. DAVID
Lenguaje:	English
Publicado:	Sociedad Chilena de Química 2007
Materias:	NNRTIs HIV-1 RT molecular modeling benzoylbenzimidazole derivatives
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072007000400002
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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