CYTOTOXIC CONSTITUENTS FROM THE ROOT WOOD OF FORMOSAN MICHELIA COMPRESSA

The methanolic extract of the root wood of Michelia compressa (Maxim.) Sargent showed cytotoxicity against MCF-7, NCI-H460 and SF-268 cancer cell lines. Bioassay-guided fractionation of the chloroform-soluble layer led to the isolation of costunohde and liriodenine with cytotoxic activities, along w...

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Autores principales: LIU,CHIA-YUAN, CHEN,YANG-WEN, CHENG,MING-JEN, LEE,SHOIW-JU, ABD EL-RAZEK,MOHAMED H, CHANG,WEN-HSIUNG, CHEN,YU-JEN, CHEN,IH-SHENG
Lenguaje:English
Publicado: Sociedad Chilena de Química 2008
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072008000200017
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spelling oai:scielo:S0717-970720080002000172009-06-09CYTOTOXIC CONSTITUENTS FROM THE ROOT WOOD OF FORMOSAN MICHELIA COMPRESSALIU,CHIA-YUANCHEN,YANG-WENCHENG,MING-JENLEE,SHOIW-JUABD EL-RAZEK,MOHAMED HCHANG,WEN-HSIUNGCHEN,YU-JENCHEN,IH-SHENG Michelia compressa Magnoliaceae root wood cytotoxicity The methanolic extract of the root wood of Michelia compressa (Maxim.) Sargent showed cytotoxicity against MCF-7, NCI-H460 and SF-268 cancer cell lines. Bioassay-guided fractionation of the chloroform-soluble layer led to the isolation of costunohde and liriodenine with cytotoxic activities, along with the isolation of twenty-seven known compounds. The active costunohde existed as major constituent in this study.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.53 n.2 20082008-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072008000200017en10.4067/S0717-97072008000200017
institution Scielo Chile
collection Scielo Chile
language English
topic Michelia compressa
Magnoliaceae
root wood
cytotoxicity
spellingShingle Michelia compressa
Magnoliaceae
root wood
cytotoxicity
LIU,CHIA-YUAN
CHEN,YANG-WEN
CHENG,MING-JEN
LEE,SHOIW-JU
ABD EL-RAZEK,MOHAMED H
CHANG,WEN-HSIUNG
CHEN,YU-JEN
CHEN,IH-SHENG
CYTOTOXIC CONSTITUENTS FROM THE ROOT WOOD OF FORMOSAN MICHELIA COMPRESSA
description The methanolic extract of the root wood of Michelia compressa (Maxim.) Sargent showed cytotoxicity against MCF-7, NCI-H460 and SF-268 cancer cell lines. Bioassay-guided fractionation of the chloroform-soluble layer led to the isolation of costunohde and liriodenine with cytotoxic activities, along with the isolation of twenty-seven known compounds. The active costunohde existed as major constituent in this study.
author LIU,CHIA-YUAN
CHEN,YANG-WEN
CHENG,MING-JEN
LEE,SHOIW-JU
ABD EL-RAZEK,MOHAMED H
CHANG,WEN-HSIUNG
CHEN,YU-JEN
CHEN,IH-SHENG
author_facet LIU,CHIA-YUAN
CHEN,YANG-WEN
CHENG,MING-JEN
LEE,SHOIW-JU
ABD EL-RAZEK,MOHAMED H
CHANG,WEN-HSIUNG
CHEN,YU-JEN
CHEN,IH-SHENG
author_sort LIU,CHIA-YUAN
title CYTOTOXIC CONSTITUENTS FROM THE ROOT WOOD OF FORMOSAN MICHELIA COMPRESSA
title_short CYTOTOXIC CONSTITUENTS FROM THE ROOT WOOD OF FORMOSAN MICHELIA COMPRESSA
title_full CYTOTOXIC CONSTITUENTS FROM THE ROOT WOOD OF FORMOSAN MICHELIA COMPRESSA
title_fullStr CYTOTOXIC CONSTITUENTS FROM THE ROOT WOOD OF FORMOSAN MICHELIA COMPRESSA
title_full_unstemmed CYTOTOXIC CONSTITUENTS FROM THE ROOT WOOD OF FORMOSAN MICHELIA COMPRESSA
title_sort cytotoxic constituents from the root wood of formosan michelia compressa
publisher Sociedad Chilena de Química
publishDate 2008
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072008000200017
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