CYTOTOXIC CONSTITUENTS FROM THE ROOT WOOD OF FORMOSAN MICHELIA COMPRESSA
The methanolic extract of the root wood of Michelia compressa (Maxim.) Sargent showed cytotoxicity against MCF-7, NCI-H460 and SF-268 cancer cell lines. Bioassay-guided fractionation of the chloroform-soluble layer led to the isolation of costunohde and liriodenine with cytotoxic activities, along w...
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Sociedad Chilena de Química
2008
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oai:scielo:S0717-970720080002000172009-06-09CYTOTOXIC CONSTITUENTS FROM THE ROOT WOOD OF FORMOSAN MICHELIA COMPRESSALIU,CHIA-YUANCHEN,YANG-WENCHENG,MING-JENLEE,SHOIW-JUABD EL-RAZEK,MOHAMED HCHANG,WEN-HSIUNGCHEN,YU-JENCHEN,IH-SHENG Michelia compressa Magnoliaceae root wood cytotoxicity The methanolic extract of the root wood of Michelia compressa (Maxim.) Sargent showed cytotoxicity against MCF-7, NCI-H460 and SF-268 cancer cell lines. Bioassay-guided fractionation of the chloroform-soluble layer led to the isolation of costunohde and liriodenine with cytotoxic activities, along with the isolation of twenty-seven known compounds. The active costunohde existed as major constituent in this study.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.53 n.2 20082008-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072008000200017en10.4067/S0717-97072008000200017 |
institution |
Scielo Chile |
collection |
Scielo Chile |
language |
English |
topic |
Michelia compressa Magnoliaceae root wood cytotoxicity |
spellingShingle |
Michelia compressa Magnoliaceae root wood cytotoxicity LIU,CHIA-YUAN CHEN,YANG-WEN CHENG,MING-JEN LEE,SHOIW-JU ABD EL-RAZEK,MOHAMED H CHANG,WEN-HSIUNG CHEN,YU-JEN CHEN,IH-SHENG CYTOTOXIC CONSTITUENTS FROM THE ROOT WOOD OF FORMOSAN MICHELIA COMPRESSA |
description |
The methanolic extract of the root wood of Michelia compressa (Maxim.) Sargent showed cytotoxicity against MCF-7, NCI-H460 and SF-268 cancer cell lines. Bioassay-guided fractionation of the chloroform-soluble layer led to the isolation of costunohde and liriodenine with cytotoxic activities, along with the isolation of twenty-seven known compounds. The active costunohde existed as major constituent in this study. |
author |
LIU,CHIA-YUAN CHEN,YANG-WEN CHENG,MING-JEN LEE,SHOIW-JU ABD EL-RAZEK,MOHAMED H CHANG,WEN-HSIUNG CHEN,YU-JEN CHEN,IH-SHENG |
author_facet |
LIU,CHIA-YUAN CHEN,YANG-WEN CHENG,MING-JEN LEE,SHOIW-JU ABD EL-RAZEK,MOHAMED H CHANG,WEN-HSIUNG CHEN,YU-JEN CHEN,IH-SHENG |
author_sort |
LIU,CHIA-YUAN |
title |
CYTOTOXIC CONSTITUENTS FROM THE ROOT WOOD OF FORMOSAN MICHELIA COMPRESSA |
title_short |
CYTOTOXIC CONSTITUENTS FROM THE ROOT WOOD OF FORMOSAN MICHELIA COMPRESSA |
title_full |
CYTOTOXIC CONSTITUENTS FROM THE ROOT WOOD OF FORMOSAN MICHELIA COMPRESSA |
title_fullStr |
CYTOTOXIC CONSTITUENTS FROM THE ROOT WOOD OF FORMOSAN MICHELIA COMPRESSA |
title_full_unstemmed |
CYTOTOXIC CONSTITUENTS FROM THE ROOT WOOD OF FORMOSAN MICHELIA COMPRESSA |
title_sort |
cytotoxic constituents from the root wood of formosan michelia compressa |
publisher |
Sociedad Chilena de Química |
publishDate |
2008 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072008000200017 |
work_keys_str_mv |
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1718445388128583680 |