A FACILE SYNTHESIS OF 6,7-FUSED STEROIDAL THIAZOLES VIA 1,3-INTRAMOLECULAR MIGRATION OF BROMINE/ALLYLIC DISPLACEMENT OF BROMINE
A facile synthesis of an array of 6,7-fused steroidal thiazoles (4-9) is reported. Replacement of lachrymatory 7-bromosteroidal ketones (4a) with readily accessible 5-bromosteroidal ketones (1-3), as a starting material, on simple condensation with thiourea or phenylthiourea gives the thiazole fused...
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Autores principales: | ALAM,MAHBOOB, KHAN,SURAIYA, SHAHEEN KHAN,MOHD |
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Lenguaje: | English |
Publicado: |
Sociedad Chilena de Química
2008
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Materias: | |
Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072008000400017 |
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