A NEW METHOD TO SYNTHESIZE 3,5-DIARYLPYRAZOL DERIVATIVES

Twelve 3, 5-diarylpyrazoles have been synthesized by microwave-assisted condensation reaction in a short and concise manner using various aromatic aldehydes and aromatic ketones as starting materials. The corresponding products were obtained in good yields (87-96%). All products were identified by M...

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Auteurs principaux: HUANG,XIANQIANG, DOU,JIANMIN, LI,DACHENG, WANG,DAQI
Langue:English
Publié: Sociedad Chilena de Química 2009
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Accès en ligne:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072009000100005
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Résumé:Twelve 3, 5-diarylpyrazoles have been synthesized by microwave-assisted condensation reaction in a short and concise manner using various aromatic aldehydes and aromatic ketones as starting materials. The corresponding products were obtained in good yields (87-96%). All products were identified by MS, ¹H NMR, 13C NMR and elemental analysis. The advantages of this novel protocol include the excellent yield, operational simplicity, short time and the avoidance of the use of expensive catalysts.