SYNTHESIS OF 2-(2-(HYDROXYMETHYL)PHENYL)ETHANOL DERIVATIVES AS POTENTIAL ANTIBACTERIAL AGENTS

SYNTHESIS OF 2-(2-(HYDROXYMETHYL)PHENYL)ETHANOL DERIVATIVES AS POTENTIAL ANTIBACTERIAL AGENTS

Reaction of 3-substituted isocoumarins (la-h) with excess of sodium borohydride in methanol gave the corresponding 2-(2-(hydroxymethyl)phenyl)ethanol derivatives (2a-h). Antimicrobial activities of synthesized compounds were measured, using Gram-negative (Escherichia coli, Salmonella typhi, Proteus...

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Autores principales: MANIVEL,P, NAWAZ KHAN,F
Lenguaje:English
Publicado: Sociedad Chilena de Química 2009
Materias:
Isocoumarin
sodium borohydride
diol
antimicrobial properties
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072009000200019
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spelling oai:scielo:S0717-970720090002000192009-10-07SYNTHESIS OF 2-(2-(HYDROXYMETHYL)PHENYL)ETHANOL DERIVATIVES AS POTENTIAL ANTIBACTERIAL AGENTSMANIVEL,PNAWAZ KHAN,F Isocoumarin sodium borohydride diol antimicrobial properties Reaction of 3-substituted isocoumarins (la-h) with excess of sodium borohydride in methanol gave the corresponding 2-(2-(hydroxymethyl)phenyl)ethanol derivatives (2a-h). Antimicrobial activities of synthesized compounds were measured, using Gram-negative (Escherichia coli, Salmonella typhi, Proteus mirabilis) and Gram-positive bacteria (Bacillus cereus, Staphylococcus aureus).info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.54 n.2 20092009-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072009000200019en10.4067/S0717-97072009000200019
institution Scielo Chile
collection Scielo Chile
language English
topic Isocoumarin
sodium borohydride
diol
antimicrobial properties
spellingShingle Isocoumarin
sodium borohydride
diol
antimicrobial properties
MANIVEL,P
NAWAZ KHAN,F
SYNTHESIS OF 2-(2-(HYDROXYMETHYL)PHENYL)ETHANOL DERIVATIVES AS POTENTIAL ANTIBACTERIAL AGENTS
description Reaction of 3-substituted isocoumarins (la-h) with excess of sodium borohydride in methanol gave the corresponding 2-(2-(hydroxymethyl)phenyl)ethanol derivatives (2a-h). Antimicrobial activities of synthesized compounds were measured, using Gram-negative (Escherichia coli, Salmonella typhi, Proteus mirabilis) and Gram-positive bacteria (Bacillus cereus, Staphylococcus aureus).
author MANIVEL,P
NAWAZ KHAN,F
author_facet MANIVEL,P
NAWAZ KHAN,F
author_sort MANIVEL,P
title SYNTHESIS OF 2-(2-(HYDROXYMETHYL)PHENYL)ETHANOL DERIVATIVES AS POTENTIAL ANTIBACTERIAL AGENTS
title_short SYNTHESIS OF 2-(2-(HYDROXYMETHYL)PHENYL)ETHANOL DERIVATIVES AS POTENTIAL ANTIBACTERIAL AGENTS
title_full SYNTHESIS OF 2-(2-(HYDROXYMETHYL)PHENYL)ETHANOL DERIVATIVES AS POTENTIAL ANTIBACTERIAL AGENTS
title_fullStr SYNTHESIS OF 2-(2-(HYDROXYMETHYL)PHENYL)ETHANOL DERIVATIVES AS POTENTIAL ANTIBACTERIAL AGENTS
title_full_unstemmed SYNTHESIS OF 2-(2-(HYDROXYMETHYL)PHENYL)ETHANOL DERIVATIVES AS POTENTIAL ANTIBACTERIAL AGENTS
title_sort synthesis of 2-(2-(hydroxymethyl)phenyl)ethanol derivatives as potential antibacterial agents
publisher Sociedad Chilena de Química
publishDate 2009
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072009000200019
work_keys_str_mv AT manivelp synthesisof22hydroxymethylphenylethanolderivativesaspotentialantibacterialagents
AT nawazkhanf synthesisof22hydroxymethylphenylethanolderivativesaspotentialantibacterialagents
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