SYNTHESIS OF 3 SUBSTITUTED ISOQUINOLIN-1-YL-2-(CYCLOALK-2-ENYLIDENE) HYDRAZINES AND THEIR ANTIMICROBIAL PROPERTIES

New hydrazine derivatives were synthesized via reaction between 1, 3 cyclic diketones and hydrazinoisoquinohne derivatives. The reaction proceeded smoothly in ethanol under reflux temperature and furnished products in excellent yields (76-87%). The products have been purified and fully characterized...

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Autores principales: MANIVEL,P, MOHANA ROOPAN,S, SATHISH KUMAR,R, NAWAZ KHAN,F
Lenguaje:English
Publicado: Sociedad Chilena de Química 2009
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072009000200020
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spelling oai:scielo:S0717-970720090002000202009-10-07SYNTHESIS OF 3 SUBSTITUTED ISOQUINOLIN-1-YL-2-(CYCLOALK-2-ENYLIDENE) HYDRAZINES AND THEIR ANTIMICROBIAL PROPERTIESMANIVEL,PMOHANA ROOPAN,SSATHISH KUMAR,RNAWAZ KHAN,F 1, 3-cyclic diketones hydrazinoisoquinohne derivatives New hydrazine derivatives were synthesized via reaction between 1, 3 cyclic diketones and hydrazinoisoquinohne derivatives. The reaction proceeded smoothly in ethanol under reflux temperature and furnished products in excellent yields (76-87%). The products have been purified and fully characterized by spectroscopy techniques. The compounds 8a-c showed good bacterial inhibition against Bacillus cerus and 8d-f showed good antifungal activity against Candida albicans.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.54 n.2 20092009-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072009000200020en10.4067/S0717-97072009000200020
institution Scielo Chile
collection Scielo Chile
language English
topic 1, 3-cyclic diketones
hydrazinoisoquinohne derivatives
spellingShingle 1, 3-cyclic diketones
hydrazinoisoquinohne derivatives
MANIVEL,P
MOHANA ROOPAN,S
SATHISH KUMAR,R
NAWAZ KHAN,F
SYNTHESIS OF 3 SUBSTITUTED ISOQUINOLIN-1-YL-2-(CYCLOALK-2-ENYLIDENE) HYDRAZINES AND THEIR ANTIMICROBIAL PROPERTIES
description New hydrazine derivatives were synthesized via reaction between 1, 3 cyclic diketones and hydrazinoisoquinohne derivatives. The reaction proceeded smoothly in ethanol under reflux temperature and furnished products in excellent yields (76-87%). The products have been purified and fully characterized by spectroscopy techniques. The compounds 8a-c showed good bacterial inhibition against Bacillus cerus and 8d-f showed good antifungal activity against Candida albicans.
author MANIVEL,P
MOHANA ROOPAN,S
SATHISH KUMAR,R
NAWAZ KHAN,F
author_facet MANIVEL,P
MOHANA ROOPAN,S
SATHISH KUMAR,R
NAWAZ KHAN,F
author_sort MANIVEL,P
title SYNTHESIS OF 3 SUBSTITUTED ISOQUINOLIN-1-YL-2-(CYCLOALK-2-ENYLIDENE) HYDRAZINES AND THEIR ANTIMICROBIAL PROPERTIES
title_short SYNTHESIS OF 3 SUBSTITUTED ISOQUINOLIN-1-YL-2-(CYCLOALK-2-ENYLIDENE) HYDRAZINES AND THEIR ANTIMICROBIAL PROPERTIES
title_full SYNTHESIS OF 3 SUBSTITUTED ISOQUINOLIN-1-YL-2-(CYCLOALK-2-ENYLIDENE) HYDRAZINES AND THEIR ANTIMICROBIAL PROPERTIES
title_fullStr SYNTHESIS OF 3 SUBSTITUTED ISOQUINOLIN-1-YL-2-(CYCLOALK-2-ENYLIDENE) HYDRAZINES AND THEIR ANTIMICROBIAL PROPERTIES
title_full_unstemmed SYNTHESIS OF 3 SUBSTITUTED ISOQUINOLIN-1-YL-2-(CYCLOALK-2-ENYLIDENE) HYDRAZINES AND THEIR ANTIMICROBIAL PROPERTIES
title_sort synthesis of 3 substituted isoquinolin-1-yl-2-(cycloalk-2-enylidene) hydrazines and their antimicrobial properties
publisher Sociedad Chilena de Química
publishDate 2009
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072009000200020
work_keys_str_mv AT manivelp synthesisof3substitutedisoquinolin1yl2cycloalk2enylidenehydrazinesandtheirantimicrobialproperties
AT mohanaroopans synthesisof3substitutedisoquinolin1yl2cycloalk2enylidenehydrazinesandtheirantimicrobialproperties
AT sathishkumarr synthesisof3substitutedisoquinolin1yl2cycloalk2enylidenehydrazinesandtheirantimicrobialproperties
AT nawazkhanf synthesisof3substitutedisoquinolin1yl2cycloalk2enylidenehydrazinesandtheirantimicrobialproperties
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