SYNTHESIS OF 3 SUBSTITUTED ISOQUINOLIN-1-YL-2-(CYCLOALK-2-ENYLIDENE) HYDRAZINES AND THEIR ANTIMICROBIAL PROPERTIES
New hydrazine derivatives were synthesized via reaction between 1, 3 cyclic diketones and hydrazinoisoquinohne derivatives. The reaction proceeded smoothly in ethanol under reflux temperature and furnished products in excellent yields (76-87%). The products have been purified and fully characterized...
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Sociedad Chilena de Química
2009
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oai:scielo:S0717-970720090002000202009-10-07SYNTHESIS OF 3 SUBSTITUTED ISOQUINOLIN-1-YL-2-(CYCLOALK-2-ENYLIDENE) HYDRAZINES AND THEIR ANTIMICROBIAL PROPERTIESMANIVEL,PMOHANA ROOPAN,SSATHISH KUMAR,RNAWAZ KHAN,F 1, 3-cyclic diketones hydrazinoisoquinohne derivatives New hydrazine derivatives were synthesized via reaction between 1, 3 cyclic diketones and hydrazinoisoquinohne derivatives. The reaction proceeded smoothly in ethanol under reflux temperature and furnished products in excellent yields (76-87%). The products have been purified and fully characterized by spectroscopy techniques. The compounds 8a-c showed good bacterial inhibition against Bacillus cerus and 8d-f showed good antifungal activity against Candida albicans.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.54 n.2 20092009-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072009000200020en10.4067/S0717-97072009000200020 |
institution |
Scielo Chile |
collection |
Scielo Chile |
language |
English |
topic |
1, 3-cyclic diketones hydrazinoisoquinohne derivatives |
spellingShingle |
1, 3-cyclic diketones hydrazinoisoquinohne derivatives MANIVEL,P MOHANA ROOPAN,S SATHISH KUMAR,R NAWAZ KHAN,F SYNTHESIS OF 3 SUBSTITUTED ISOQUINOLIN-1-YL-2-(CYCLOALK-2-ENYLIDENE) HYDRAZINES AND THEIR ANTIMICROBIAL PROPERTIES |
description |
New hydrazine derivatives were synthesized via reaction between 1, 3 cyclic diketones and hydrazinoisoquinohne derivatives. The reaction proceeded smoothly in ethanol under reflux temperature and furnished products in excellent yields (76-87%). The products have been purified and fully characterized by spectroscopy techniques. The compounds 8a-c showed good bacterial inhibition against Bacillus cerus and 8d-f showed good antifungal activity against Candida albicans. |
author |
MANIVEL,P MOHANA ROOPAN,S SATHISH KUMAR,R NAWAZ KHAN,F |
author_facet |
MANIVEL,P MOHANA ROOPAN,S SATHISH KUMAR,R NAWAZ KHAN,F |
author_sort |
MANIVEL,P |
title |
SYNTHESIS OF 3 SUBSTITUTED ISOQUINOLIN-1-YL-2-(CYCLOALK-2-ENYLIDENE) HYDRAZINES AND THEIR ANTIMICROBIAL PROPERTIES |
title_short |
SYNTHESIS OF 3 SUBSTITUTED ISOQUINOLIN-1-YL-2-(CYCLOALK-2-ENYLIDENE) HYDRAZINES AND THEIR ANTIMICROBIAL PROPERTIES |
title_full |
SYNTHESIS OF 3 SUBSTITUTED ISOQUINOLIN-1-YL-2-(CYCLOALK-2-ENYLIDENE) HYDRAZINES AND THEIR ANTIMICROBIAL PROPERTIES |
title_fullStr |
SYNTHESIS OF 3 SUBSTITUTED ISOQUINOLIN-1-YL-2-(CYCLOALK-2-ENYLIDENE) HYDRAZINES AND THEIR ANTIMICROBIAL PROPERTIES |
title_full_unstemmed |
SYNTHESIS OF 3 SUBSTITUTED ISOQUINOLIN-1-YL-2-(CYCLOALK-2-ENYLIDENE) HYDRAZINES AND THEIR ANTIMICROBIAL PROPERTIES |
title_sort |
synthesis of 3 substituted isoquinolin-1-yl-2-(cycloalk-2-enylidene) hydrazines and their antimicrobial properties |
publisher |
Sociedad Chilena de Química |
publishDate |
2009 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072009000200020 |
work_keys_str_mv |
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1718445404730687488 |