SECONDARY METABOLITES FROM THE CULTURE BROTH OF ACTINOMYCETE ACROCARPOSPORA SP. FIRDI 001 AND THEIR ANTIMICROBIAL ACTIVITY

Two natural new compounds, pyrroline-2-one (1) and 2-(2-amino-3-methyl-butyrylamino)-3-(4-hydroxy-phenyl)-propionic acid (2), together with nine known compounds, iodinin (3), thymine (4), V-(2-hydroxy-phenyl)-acetamide (5), (Z)-pulchellalactam (6), uracil (7), nicotinic acid (8), nicotiamide (9); p-...

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Autores principales:	CHENG,MING-JEN, TSENG,MIN, CHEN,IH-SHENG, LIAO,CHII-CHERNG, YUAN,GWO-FANG
Lenguaje:	English
Publicado:	Sociedad Chilena de Química 2009
Materias:	Acrocarpospora sp Actinomycetes Secondary metabolites alkaloids Iodinin Antimicrobial activity
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072009000200024
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spelling	oai:scielo:S0717-970720090002000242009-10-07SECONDARY METABOLITES FROM THE CULTURE BROTH OF ACTINOMYCETE ACROCARPOSPORA SP. FIRDI 001 AND THEIR ANTIMICROBIAL ACTIVITYCHENG,MING-JENTSENG,MINCHEN,IH-SHENGLIAO,CHII-CHERNGYUAN,GWO-FANG Acrocarpospora sp Actinomycetes Secondary metabolites alkaloids Iodinin Antimicrobial activity Two natural new compounds, pyrroline-2-one (1) and 2-(2-amino-3-methyl-butyrylamino)-3-(4-hydroxy-phenyl)-propionic acid (2), together with nine known compounds, iodinin (3), thymine (4), V-(2-hydroxy-phenyl)-acetamide (5), (Z)-pulchellalactam (6), uracil (7), nicotinic acid (8), nicotiamide (9); p-nitrophenol (10) and indole 3-carboxylic acid (11), all were isolated from the EtOAc extract of the culture broth of anew actinomycete Acrocarpospora sp. strain, FIRDI 001. The structures were elucidated by ID and 2D NMR spectroscopy and mass spectrometry. Furthermore, the isolated compounds were subjected to evaluate the antimicrobial activity. Compounds 2, 3 and 10 showed antimicrobial activity. The active metabolite, iodinin existed as a major metabolite in this study.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.54 n.2 20092009-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072009000200024en10.4067/S0717-97072009000200024
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Acrocarpospora sp Actinomycetes Secondary metabolites alkaloids Iodinin Antimicrobial activity
spellingShingle	Acrocarpospora sp Actinomycetes Secondary metabolites alkaloids Iodinin Antimicrobial activity CHENG,MING-JEN TSENG,MIN CHEN,IH-SHENG LIAO,CHII-CHERNG YUAN,GWO-FANG SECONDARY METABOLITES FROM THE CULTURE BROTH OF ACTINOMYCETE ACROCARPOSPORA SP. FIRDI 001 AND THEIR ANTIMICROBIAL ACTIVITY
description	Two natural new compounds, pyrroline-2-one (1) and 2-(2-amino-3-methyl-butyrylamino)-3-(4-hydroxy-phenyl)-propionic acid (2), together with nine known compounds, iodinin (3), thymine (4), V-(2-hydroxy-phenyl)-acetamide (5), (Z)-pulchellalactam (6), uracil (7), nicotinic acid (8), nicotiamide (9); p-nitrophenol (10) and indole 3-carboxylic acid (11), all were isolated from the EtOAc extract of the culture broth of anew actinomycete Acrocarpospora sp. strain, FIRDI 001. The structures were elucidated by ID and 2D NMR spectroscopy and mass spectrometry. Furthermore, the isolated compounds were subjected to evaluate the antimicrobial activity. Compounds 2, 3 and 10 showed antimicrobial activity. The active metabolite, iodinin existed as a major metabolite in this study.
author	CHENG,MING-JEN TSENG,MIN CHEN,IH-SHENG LIAO,CHII-CHERNG YUAN,GWO-FANG
author_facet	CHENG,MING-JEN TSENG,MIN CHEN,IH-SHENG LIAO,CHII-CHERNG YUAN,GWO-FANG
author_sort	CHENG,MING-JEN
title	SECONDARY METABOLITES FROM THE CULTURE BROTH OF ACTINOMYCETE ACROCARPOSPORA SP. FIRDI 001 AND THEIR ANTIMICROBIAL ACTIVITY
title_short	SECONDARY METABOLITES FROM THE CULTURE BROTH OF ACTINOMYCETE ACROCARPOSPORA SP. FIRDI 001 AND THEIR ANTIMICROBIAL ACTIVITY
title_full	SECONDARY METABOLITES FROM THE CULTURE BROTH OF ACTINOMYCETE ACROCARPOSPORA SP. FIRDI 001 AND THEIR ANTIMICROBIAL ACTIVITY
title_fullStr	SECONDARY METABOLITES FROM THE CULTURE BROTH OF ACTINOMYCETE ACROCARPOSPORA SP. FIRDI 001 AND THEIR ANTIMICROBIAL ACTIVITY
title_full_unstemmed	SECONDARY METABOLITES FROM THE CULTURE BROTH OF ACTINOMYCETE ACROCARPOSPORA SP. FIRDI 001 AND THEIR ANTIMICROBIAL ACTIVITY
title_sort	secondary metabolites from the culture broth of actinomycete acrocarpospora sp. firdi 001 and their antimicrobial activity
publisher	Sociedad Chilena de Química
publishDate	2009
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072009000200024
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SECONDARY METABOLITES FROM THE CULTURE BROTH OF ACTINOMYCETE ACROCARPOSPORA SP. FIRDI 001 AND THEIR ANTIMICROBIAL ACTIVITY

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