IMPROVEMENT OF GALANGIN SOLUBILITY USING NATIVE AND DERIVATIVE CYCLODEXTRINS: AN UV-Vis AND NMR STUDY
The slightly water-soluble flavonoid galangin (G) and its inclusion with either β-cyclodextrin (βCD), hydro xypropyl-β-cyclodextrin (HPβCD) or Heptakis-2,6-O-di methyl-β-cyclodextrin (DMβCD) were investigated. The stoichiometric ratios and stabil...
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Sociedad Chilena de Química
2009
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oai:scielo:S0717-970720090002000252009-10-07IMPROVEMENT OF GALANGIN SOLUBILITY USING NATIVE AND DERIVATIVE CYCLODEXTRINS: AN UV-Vis AND NMR STUDYJULLIAN,CAROLINA cyclodextrin galangin NMR The slightly water-soluble flavonoid galangin (G) and its inclusion with either β-cyclodextrin (βCD), hydro xypropyl-β-cyclodextrin (HPβCD) or Heptakis-2,6-O-di methyl-β-cyclodextrin (DMβCD) were investigated. The stoichiometric ratios and stability constants describing the extent of the formation of the complexes have been determined by phase-solubility measurements; in all cases type-A L diagrams have been obtained (soluble 1:1 complexes). The results showed that the complex efficiency of βCD and its derivatives was the order: DMβCD > HPβCD > βCD. The NMR study indicate that the inclusion of galangin in the cyclodextrin nano-cavity is different depending on the type of cyclodextrin used.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.54 n.2 20092009-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072009000200025en10.4067/S0717-97072009000200025 |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
English |
| topic |
cyclodextrin galangin NMR |
| spellingShingle |
cyclodextrin galangin NMR JULLIAN,CAROLINA IMPROVEMENT OF GALANGIN SOLUBILITY USING NATIVE AND DERIVATIVE CYCLODEXTRINS: AN UV-Vis AND NMR STUDY |
| description |
The slightly water-soluble flavonoid galangin (G) and its inclusion with either β-cyclodextrin (βCD), hydro xypropyl-β-cyclodextrin (HPβCD) or Heptakis-2,6-O-di methyl-β-cyclodextrin (DMβCD) were investigated. The stoichiometric ratios and stability constants describing the extent of the formation of the complexes have been determined by phase-solubility measurements; in all cases type-A L diagrams have been obtained (soluble 1:1 complexes). The results showed that the complex efficiency of βCD and its derivatives was the order: DMβCD > HPβCD > βCD. The NMR study indicate that the inclusion of galangin in the cyclodextrin nano-cavity is different depending on the type of cyclodextrin used. |
| author |
JULLIAN,CAROLINA |
| author_facet |
JULLIAN,CAROLINA |
| author_sort |
JULLIAN,CAROLINA |
| title |
IMPROVEMENT OF GALANGIN SOLUBILITY USING NATIVE AND DERIVATIVE CYCLODEXTRINS: AN UV-Vis AND NMR STUDY |
| title_short |
IMPROVEMENT OF GALANGIN SOLUBILITY USING NATIVE AND DERIVATIVE CYCLODEXTRINS: AN UV-Vis AND NMR STUDY |
| title_full |
IMPROVEMENT OF GALANGIN SOLUBILITY USING NATIVE AND DERIVATIVE CYCLODEXTRINS: AN UV-Vis AND NMR STUDY |
| title_fullStr |
IMPROVEMENT OF GALANGIN SOLUBILITY USING NATIVE AND DERIVATIVE CYCLODEXTRINS: AN UV-Vis AND NMR STUDY |
| title_full_unstemmed |
IMPROVEMENT OF GALANGIN SOLUBILITY USING NATIVE AND DERIVATIVE CYCLODEXTRINS: AN UV-Vis AND NMR STUDY |
| title_sort |
improvement of galangin solubility using native and derivative cyclodextrins: an uv-vis and nmr study |
| publisher |
Sociedad Chilena de Química |
| publishDate |
2009 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072009000200025 |
| work_keys_str_mv |
AT julliancarolina improvementofgalanginsolubilityusingnativeandderivativecyclodextrinsanuvvisandnmrstudy |
| _version_ |
1718445405723688960 |